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PYRAZINAMIDE [PZA]


pncA: Rv2043c

Rv2043c

More about Rv2043c on    TBDB.org

More about Rv2043c on    TubercuList

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Codons 280 to 299:1 Mutation Codons 240 to 259:1 Mutation Codons 180 to 199:5 Mutation Codons 160 to 179:17 Mutation Codons 140 to 159:29 Mutation Codons 120 to 139:45 Mutation Codons 100 to 119:23 Mutation Codons 80 to 99:24 Mutation Codons 60 to 79:34 Mutation Codons 40 to 59:39 Mutation Codons 20 to 39:18 Mutation Codons 0 to 19:42 Mutation
Select interval to show only those mutations included. Selected interval is marked with a red color.
IDSeqNoAdded byPrimary referencePolymorphismNucleotide positionCodon positionAmino acidTime periodOriginMolecular detection methodGene coverageResistance patternMICSusceptibility testing methodR/Total isolatesR/S isolates with mutationAdditional mutationsEditDeleteHigh confidence supportSelect
5451 Marttila HJ AAC 1999 T/G-12-12 1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested   
5462 Scorpio A AAC 1997 A/C-11-11 1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
5473 Sreevatsan S AAC 1997 A/G-11-11 1996Diverse geographical locationsSequencingWhole geneZ BACTEC 460 67/1182/0  High confidence details 
5484 Morlock GP AAC 2000 T/C-7-7 1999 SequencingWhole geneZ100Proportion method37/601/0    
59753 Hannan MM JCM 2001 del 24bp88-112 Frameshift1996-1999California, USASequencingWhole geneZ BACTEC radiometric testing398831/0    
59854 Scorpio A AAC 1997 del 118bp98-216 Frameshift1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
60460 Morlock GP AAC 2000 del 5.3kb106 Frameshift/Truncation1999 SequencingWhole geneZ800Proportion method37/601/0    
62379 Lee KW J Korean Med Sci 2001 del 80bp151-230 Frameshift2001South KoreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
652108 Mestdagh M AAC 1999 del 68bp195-263 Frameshift1999AzerbaijanSequencingWhole geneZ BACTEC 460 23/621/0    
670126 Lemaitre N AAC 1999 ins 29bp215 Frameshift1986FranceSequencingWhole geneZHRS>2000 19/351/0    
671127 Sekiguchi JI JCM 2007 ins CGCATTGCCG218 Frameshift2006 Multi-plex PCRWhole geneZ Proportion method, rapid broth method17/1381/0    
678134 Brown TJ JMedMicro 2000 del A239 Frameshift2000TurkeySequencingWhole geneZ BACTEC 460 13/181/0C2431T (rpoB)   
683139 Peridgao J MDR 2008 ins C250 Frameshift2003PortugalSequencingWhole geneZHRS MGIT 96048/583/0    
691147 Peridgao J MDR 2008 ins T282 Frameshift2003PortugalSequencingWhole geneZHRS MGIT 96048/581/0    
696152 Hirano K TLD 1997 ins T287 Frameshift1997CanadaSequencingWhole geneZHRS>800Proportion method33/1681/0    
697153 Lee KW J Korean Med Sci 2001 ins T287 Frameshift2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
699155 Scorpio A Nature Med 1996 del G288 Frameshift USASequencingWhole geneZ>500ug/mlPZase test with Wayne's method399101/0    
704160 Cheng SJ AAC 2000 ins G301 Frameshift South koreaSequencingWhole geneZ>500Proportion method, BACTEC 46059/591/0    
705161 Hou L Epi Infect 2000 ins A301 Frameshift1996-1998ChinaPCR-SSCPWhole geneZHRS900Proportion method, BACTEC 46035/651/0    
708164 Lemaitre N AAC 1999 ins C306 Frameshift1989FranceSequencingWhole geneZHRES500-1500 19/351/0    
710166 Lee KW J Korean Med Sci 2001 del TACAG307 Frameshift2001South KoreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
719175 Cheng SJ AAC 2000 del C341 Frameshift South KoreaSequencingWhole geneZ>500Proportion method, BACTEC 46059/591/0?    
720176 Lemaitre N AAC 1999 ins 1355bp341 Frameshift1989FranceSequencingWhole geneZHRE1000 19/351/0    
729185 Hou L Epi Infect 2000 ins AG368 Frameshift1996-1998ChinaPCR-SSCPWhole geneZRHSE1000Proportion method, BACTEC 46035/651/0    
730186 Lee KW J Korean Med Sci 2001 ins 18bp368 Frameshift2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
733189 Marttila HJ AAC 1999 del 11bp379-389 Frameshift1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested   
734190 Lee KW J Korean Med Sci 2001 del GG381 Frameshift2001South KoreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
735191 Peridgao J MDR 2008 del 9bp381 Frameshift2003PortugalSequencingWhole geneZHRS MGIT 96048/581/0    
736192 Lee KW J Korean Med Sci 2001 ins AG382 Frameshift2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
738194 Lee KW J Korean Med Sci 2001 del ATGT386-389 Frameshift2001South KoreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
739195 Morlock GP AAC 2000 ins GAGGTCGAT388 ins Glu Val Asp1999 SequencingWhole geneZ>800Proportion method37/601/0    
740196 Sreevatsan S AAC 1997 ins AGGTCGATG388 Ins Arg Ser Met1996Diverse geographical locationsSequencingWhole geneZ BACTEC 46067/1184/0  High confidence details 
742198 Lee KW J Korean Med Sci 2001 ins GG391 Frameshift2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
743199 Lemaitre N AAC 1999 ins GG391 Frameshift1988FranceSequencingWhole geneZHRES500-1000 19/351/0    
744200 Scorpio A AAC 1997 del G391 Frameshift1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
745201 Lee KW J Korean Med Sci 2001 ins G392 Frameshift2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
748204 Hirano K TLD 1997 del 16bp395-411 del Frameshift1997IndiaSequencingWhole geneZR>800Proportion method33/1681/0    
749205 Sreevatsan S AAC 1997 ins T397 Frameshift1996Diverse geographical locationsSequencingWhole geneZ BACTEC 46067/1181/0    
754210 Hou L Epi Infect 2000 ins CC403 Frameshift1996-1998ChinaPCR-SSCPWhole geneZRE1000Proportion method, BACTEC 46035/651/0    
755211 Sreevatsan S AAC 1997 ins C403 Frameshift1996Diverse geographical locationsSequencingWhole geneZ BACTEC 46067/1181/0    
759215 Lee KW J Korean Med Sci 2001 del G406 Frameshift2001South KoreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
761217 Mestdagh M AAC 1999 ins C407-408 Frameshift1999AzerbaijanSequencingWhole geneZ BACTEC 460 23/621/0    
766222 Lee KW J Korean Med Sci 2001 ins G414 Frameshift2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
771227 Scorpio A AAC 1997 del TG416 Frameshift1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
773229 Lemaitre N AAC 1999 del 68bp419 Frameshift1992FranceSequencingWhole geneZHRE1000 19/351/0    
774230 Cheng SJ AAC 2000 ins G420 Frameshift USASequencingWhole geneZR>900Proportion method, BACTEC 46059/591/0    
775231 Cheng SJ AAC 2000 ins GG420 Frameshift USASequencingWhole geneZHRSO>900Proportion method, BACTEC 46059/591/0    
782238 Cheng SJ AAC 2000 ins GG428 Frameshift South koreaSequencingWhole geneZ>100Proportion method, BACTEC 46059/591/0?    
784240 Lemaitre N AAC 1999 del G436 Frameshift1987FranceSequencingWhole geneZHRE1000-1500 19/351/0    
786242 Peridgao J MDR 2008 ins CG439 Frameshift2003PortugalSequencingWhole geneZHRS MGIT 96048/581/0    
789245 Scorpio A AAC 1997 del G443 Frameshift1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
790246 Cheng SJ AAC 2000 del 8bp446 Frameshift1990-1992CanadaSequencingWhole geneZHRE>300Proportion method, BACTEC 46059/591/0    
791247 Scorpio A AAC 1997 ins 8bp446 Frameshift1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
792248 Lee KW J Korean Med Sci 2001 del T452 Frameshift2001South KoreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
797253 Lee KW J Korean Med Sci 2001 ins T465 Frameshift2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/952/0    
798254 Scorpio A AAC 1997 del C475 Frameshift1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
802258 Lee KW J Korean Med Sci 2001 ins TGAC480 Frameshift2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
805261 Hou L Epi Infect 2000 ins CG501 Frameshift1996-1998ChinaPCR-SSCPWhole geneZSHE900Proportion method, BACTEC 46035/651/0    
811267 Mestdagh M AAC 1999 del C512 Frameshift1999RwandaSequencingWhole geneZ BACTEC 460 23/621/0    
814270 Scorpio A AAC 1997 ins 5bp518 Frameshift1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
816272 Lee KW J Korean Med Sci 2001 ins C532 Frameshift2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
5495 Hou L Epi Infect 2000 del 8bp11Frameshift1996-1998ChinaPCR-SSCPWhole geneZRHSE>2000Proportion method, BACTEC 46035/651/0    
5506 Scorpio A AAC 1997 del 11bp11Frameshift1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/462/0    
5517 Portugal I AAC 2004 ATG/ACG21Met/Thr2000-2001PortugalSequencingWhole geneZ BACTEC MGIT 9605555    
5528 Lee KW J Korean Med Sci 2001 ATG/ATT31Met/Ile2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
5539 Lemaitre N AAC 1999 GCG/CCG73Ala/Pro1986FranceSequencingWhole geneZHR1000  1/0  High confidence details 
55410 Sekiguchi JI JCM 2007 GCG/GAG83Ala/Glu2006JapanMulti-plex PCRWhole geneZ Proportion method, rapid broth method17/1381/0  High confidence details 
55511 Lee KW J Korean Med Sci 2001 TTG/TGG114Leu/Trp2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
55612 Morlock GP AAC 2000 TTG/TCG114Leu/Ser1999 SequencingWhole geneZ800Proportion method37/601/0    
55713 Scorpio A AAC 1997 ATC/AGC145Ile/Ser1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
55814 Escalante P TuberLung Dis 1998 GTC/ATC197Val/Ile1995, 1996PeruSequencingWhole geneZHRPES Proportion method401461/0katG, 315, AGC/ACC; rpoB, 531, TCG/TTG;   
55915 Escalante P TuberLung Dis 1998 GTC/TTC197Val/Phe1995, 1996PeruSequencingWhole geneZHRPS Proportion method401461/0katG, 315, AGC/ACC; rpoB, 531, TCG/TTG; embB, 328, GAT:A del   
56016 Hirano K TLD 1997 GTC/GGC207Val/Gly1997YemenSequencingWhole geneZHRSE>800Proportion method33/1682/0  High confidence details 
56117 Lee KW J Korean Med Sci 2001 GTC/GAC207Val/Asp2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
56218 Marttila HJ AAC 1999 GAC/TAC228Asp/Tyr1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested   
56319 Lee KW J Korean Med Sci 2001 GAC/GGC238Asp/Gly2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0  High confidence details 
56420 Scorpio A AAC 1997 GAC/GAG248Asp/Glu1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
56521 Lee KW J Korean Med Sci 2001 GTG/GCG269Val/Ala2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0  High confidence details 
56622 Lee KW J Korean Med Sci 2001 GTG/GGG269Val/Gly2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0  High confidence details 
56723 Louw GE Int J Tuberc Lung Dis 2006 GTG/TTG269Val/Leu2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568    
56824 Chan RCY JAC 2007 GTG/TCG279Val/Ser1994-2004Hong KongPCR-SSCP , SequencingWhole geneZ BACTEC MGIT 96025089    
56925 Scorpio A AAC 1997 del C2810Frameshift1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
57026 Marttila HJ AAC 1999 CAA/AAA2810Gln/Lys1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested   
57127 Marttila HJ AAC 1999 CAA/TAA2810Gln/STOP1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested   
57228 Cheng SJ AAC 2000 CAG/CGA2910Gln/Arg1990-1992USASequencingWhole geneZHREO>900Proportion method, BACTEC 46059/591/0    
57329 Hirano K TLD 1997 CAG/CCG2910Gln/Pro1997MyanmarSequencingWhole geneZHRSE>800Proportion method33/1681/0  High confidence details 
57430 Morlock GP AAC 2000 CAG/CCA2910Gln/Pro1999 SequencingWhole geneZ800Proportion method37/601/0    
57531 Scorpio A AAC 1997 GAC/AAC3412Asp/Asn1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
57632 Scorpio A AAC 1997 GAC/GCC3512Asp/Ala1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0  High confidence details 
57733 Lemaitre N AAC 1999 TTC/TCC 3813Phe/Ser1987FranceSequencingWhole geneZHRES>2000 19/351/0    
57834 Scorpio A AAC 1997 TGC/CGC4014Cys/Arg1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0  High confidence details 
57935 Louw GE Int J Tuberc Lung Dis 2006 TGC/CGC4014Cys/His2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568  High confidence details 
58036 Lee KW J Korean Med Sci 2001 TGC/TAC4114Cys/Tyr2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
58137 Chan RCY JAC 2007 del G4716Frameshift1994-2004Hong KongPCR-SSCP, SequencingWhole geneZ BACTEC MGIT 96025089    
58238 Hirano K TLD 1997 GGC/GAC5017Gly/Asp1997ThailandSequencingWhole geneZHRS>800Proportion method33/1682/0  High confidence details 
58339 Chan RCY JAC 2007 GGC/GTC5017Gly/Val1994-2004Hong KongPCR-SSCP , SequencingWhole geneZ BACTEC MGIT 96025089    
58440 Cheng SJ AAC 2000 ins GG5217Frameshift USASequencingWhole geneZHR>900Proportion method, BACTEC 46059/591/0    
58541 Chan RCY JAC 2007 CTG/CGG5619Leu/Arg1994-2004Hong KongPCR-SSCP , SequencingWhole geneZ BACTEC MGIT 96025089  High confidence details 
58642 Sreevatsan S AAC 1997 CTG/CCG5619Leu/Pro1996Diverse geographical locationsSequencingWhole geneZ BACTEC 460 67/1181/0  High confidence details 
58945 Hou L Epi Infect 2000 del C5920Frameshift1996-1998ChinaPCR-SSCPWhole geneZRSE1800Proportion method, BACTEC 46035/651/0    
58743 Chan RCY JAC 2007 GTA/GGA6221Val/Gly1994-2004Hong KongPCR-SSCP , SequencingWhole geneZ BACTEC MGIT 96025089  High confidence details 
58844 Chan RCY JAC 2007 del A6422Frameshift1994-2004Hong KongPCR-SSCP, SequencingWhole geneZ BACTEC MGIT 96025089    
59046 Lee KW J Korean Med Sci 2001 GGT/GTC68-6923Gly/Val2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
59147 Sreevatsan S AAC 1997 del G7024Frameshift1996Diverse geographical locationsSequencingWhole geneZ BACTEC 46067/1187/0    
59248 Hou L Epi Infect 2000 del G7124Frameshift1996-1998ChinaPCR-SSCPWhole geneZRH600Proportion method, BACTEC 46035/651/0    
59349 Lee KW J Korean Med Sci 2001 GCC/GAA74-7525Ala/Glu2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
59450 Scorpio A AAC 1997 GCG/GGG7726Ala/Gly1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
59551 Marttila HJ AAC 1999 del C8428Frameshift1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested   
59652 Lee KW J Korean Med Sci 2001 GCC/GAC8328Ala/Asp2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
59955 Scorpio A AAC 1997 ins T10034Frameshift1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
60056 Hirano K TLD 1997 TAC/TCC10134Tyr/Ser1997ThailandSequencingWhole geneZHRSE>800Proportion method33/1682/0  High confidence details 
60157 Stavrum R PlosOne 2009 CTG/CCG10435Leu/ProPublished 2009IndiaSequencingWhole gene  N.S. 1/0  High confidence details 
60258 Louw GE Int J Tuberc Lung Dis 2006 CTG/CGG10435Leu/Arg2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568  High confidence details 
60359 Louw GE Int J Tuberc Lung Dis 2006 GGA/TAA109-11037Glu/STOP2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568    
60561 Hou L Epi Infect 2000 TAC/CAC12141Tyr/His1996-1998ChinaPCR-SSCPWhole geneZHRE600Proportion method, BACTEC 46035/651/0    
60662 Hirano K TLD 1997 TAC/TAA12341Tyr/STOP1997ThailandSequencingWhole geneZHRSE>800Middlebrook 7H11 agar w/ pH of 6.033/1681/0    
60763 Sreevatsan S AAC 1997 TAC/TAG12341Tyr/STOP1996Diverse geographical locationsSequencingWhole geneZ BACTEC 46067/1181/0  High confidence details 
60864 Hirano K TLD 1997 CAC/CCC12843His/Pro1997ThailandSequencingWhole geneZHR>800Proportion method33/1681/0  High confidence details 
60965 Lee KW J Korean Med Sci 2001 GTG/GGG13445Val/Gly2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0  High confidence details 
61066 Hirano K TLD 1997 ins G13646Frameshift1997YemenSequencingWhole geneZHE>800Proportion method33/1681/0    
61167 Louw GE Int J Tuberc Lung Dis 2006 GCA/CCA13646Ala/Pro2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568    
61268 Cheng SJ AAC 2000 GCA/GAA13746Ala/Glu South koreaSequencingWhole geneZ>500Proportion method, BACTEC 46059/591/0    
61369 Cheng SJ AAC 2000 GCA/GTA13746Ala/Val South koreaSequencingWhole geneZ>500Proportion method, BACTEC 46059/591/0  High confidence details 
61470 Hou L Epi Infect 2000 ACC/CCC13947Thr/Pro1996-1998ChinaPCR-SSCPWhole geneZRSE1500Proportion method, BACTEC 46035/651/0    
61571 Marttila HJ AAC 1999 ACC/TCC13947Thr/Ser1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested   
61672 Sreevatsan S AAC 1997 ACC/GCC13947Thr/Ala1996Diverse geographical locationsSequencingWhole geneZ BACTEC 46067/11811/0  High confidence details 
61773 Louw GE Int J Tuberc Lung Dis 2006 GAC/CAC14549Asp/His2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568    
61874 Lee KW J Korean Med Sci 2001 GAC/GCC14649Asp/Ala2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0  High confidence details 
61975 Marttila HJ AAC 1999 GAC/GTC14649Asp/Val1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested   
62076 Marttila HJ AAC 1999 GAC/GGC14649Asp/Gly1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested High confidence details 
62177 Rodrigues V de F AAC 2005 CAC/AAC15151His/Asn1998-2003BrazilSequencingWhole geneZ Proportion method5940    
62278 Mestdagh M AAC 1999 CAC/TAC15151His/Tyr1999ScotlandSequencingWhole geneZ BACTEC 460 23/621/0  High confidence details 
62480 Hirano K TLD 1997 CAC/CCC15251His/Pro1997ThailandSequencingWhole geneZHR>800Proportion method33/1681/0  High confidence details 
62581 Hirano K TLD 1997 CAC/CGC15251His/Arg1997ThailandSequencingWhole geneZHR>800Proportion method33/1681/0  High confidence details 
62682 Sekiguchi JI JCM 2007 CAC/CAG15351His/Gln2006PolandMulti-plex PCRWhole geneZ Proportion method, rapid broth method17/1381/0    
62783 Sekiguchi JI JCM 2007 CAC/CAA15351His/Gln2006JapanMulti-plex PCRWhole geneZ Proportion method, rapid broth method17/1382/0    
62884 Sekiguchi JI JCM 2007 GAC/AAC15153Asp/Asn2006JapanMulti-plex PCRWhole geneZ Proportion method, rapid broth method17/1381/0    
62985 Cheng SJ AAC 2000 GAC/GCC15853Asp/Ala South koreaSequencingWhole geneZ>100Proportion method, BACTEC 46059/591/0  High confidence details 
63086 Lee KW J Korean Med Sci 2001 del A15853Frameshift2001South KoreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
63187 Sreevatsan S AAC 1997 CCG/ACG16054Pro/Thr1996Diverse geographical locationsSequencingWhole geneZ BACTEC 46067/1181/0  High confidence details 
63288 Louw GE Int J Tuberc Lung Dis 2006 CCG/CTG16154Pro/Leu2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568    
63389 Lee KW J Korean Med Sci 2001 del C16154Frameshift2001South KoreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
63490 Scorpio A AAC 1997 ins T16254Frameshift1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
63591 Scorpio A Nature Med 1996 del G16254Frameshift USASequencingWhole geneMDR>500ug/ml7H9 liquid medium, pH5.6; PZase activity assayed according to Wayne's method 399101/0    
63692 Louw GE Int J Tuberc Lung Dis 2006 CAC/TAC16957His/Tyr2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568  High confidence details 
63793 Sreevatsan S AAC 1997 CAC/GAC16957His/Asp1996Diverse geographical locationsSequencingWhole geneZ BACTEC 46067/1182/0    
63894 Brown TJ JMedMicro 2000 CAC/CCC17057His/Pro2000TurkeySequencingWhole geneZHRP BACTEC radiometric-based culture method, standard protocol; and PZase activity13/181/0A2416T (rpoB) High confidence details 
63995 Chan RCY JAC 2007 CAC/CTC17057His/Leu1994-2004Hong KongPCR-SSCP , SequencingWhole geneZ BACTEC MGIT 96025089    
64096 Louw GE Int J Tuberc Lung Dis 2006 del T17258Frameshift2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568    
64197 Escalante P TuberLung Dis 1998 TTC/CTC17258Phe/Leu1995-1996PeruSequencingWhole geneZHR Proportion method401461/0katG, 315, AGC/ACC; rpoB, 526 cac/ctc; embB, 306, ATG/ATA   
64298 Hirano K TLD 1997 TTC/TTG17458Phe/Leu1997CanadaSequencingWhole geneZHRS400Proportion method33/1681/0    
64399 Brown TJ JMedMicro 2000 TCC/CCC17559Ser/Pro2000TurkeySequencingWhole geneZHRP BACTEC 460 13/181/0C2431T (rpoB)   
644100 Lemaitre N AAC 1999 ACA/CCA18161Thr/Pro1992FranceSequencingWhole geneZHRES500ug/ml 19/351/0  High confidence details 
645101 Mestdagh M AAC 1999 CCG/CAG??18562Pro/His 1999AzerbaijanSequencingWhole geneZ BACTEC 460 23/621/0    
646102 Morlock GP AAC 2000 CCG/CGG18562Pro/Arg1999 SequencingWhole geneZ>800Proportion method37/601/0    
647103 Chan RCY JAC 2007 CCG/CTG18662Pro/Leu1994-2004Hong KongPCR-SSCP , SequencingWhole geneZ BACTEC MGIT 96025089    
648104 Hirano K TLD 1997 GAC/GGC18863Asp/Gly1997YemenSequencingWhole geneZHRS>800Proportion method33/1681/0  High confidence details 
649105 Scorpio A Nature Med 1996 GAC/CAC18763Asp/His USA (Colorado)SequencingWhole geneMDR>500ug/mlPZase test with Wayne's method399101/0    
650106 Lee KW J Korean Med Sci 2001 TAT/GAT19064Tyr/Asp2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
651107 Lemaitre N AAC 1999 ins A19264Frameshift1996FranceSequencingWhole geneZSHE1000ug/ml  1/0    
653109 Marttila HJ AAC 1999 TCG/CCG19666Ser/Pro1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested High confidence details 
654110 Hirano K TLD 1997 TCG/CCG19967Ser/Pro1997CanadaSequencingWhole geneZHRSE>800Proportion method33/1681/0  High confidence details 
655111 Lee KW J Korean Med Sci 2001 TGG/CGG20268Trp/Arg2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0  High confidence details 
656112 Lee KW J Korean Med Sci 2001 TGG/GGG20268Trp/Gly2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0  High confidence details 
657113 Cheng SJ AAC 2000 TGG/TCA20368Trp/STOP USASequencingWhole geneZ>900Proportion method, BACTEC 46059/591/0    
658114 Lee KW J Korean Med Sci 2001 TGG/TCG20368Trp/Ser2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
659115 Sreevatsan S AAC 1997 TGG/TTG20368Trp/Leu1996Diverse geographical locationsSequencingWhole geneZ BACTEC 46067/1181/0  High confidence details 
660116 Scorpio A AAC 1997 CCA/CGA20669Pro/Arg1992-1995 PCR-SSCPWhole geneZ>300ug/mlPzase testing by Wayne's method46/462/0    
661117 Hou L Epi Infect 2000 CCA/CGA20669Pro/Arg1996-1998ChinaPCR-SSCPWhole geneZRHSE1200Proportion method, BACTEC 46035/651/0    
662118 Lemaitre N AAC 1999 CCA/CTA 20669Pro/Leu1994FranceSequencingWhole geneZHR(pH 5.6, 5.8) >2000/>2000 19/351/0    
663119 Louw GE Int J Tuberc Lung Dis 2006 CAT/TAT21171His/Tyr2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568    
664120 Louw GE Int J Tuberc Lung Dis 2006 CAT/GAT21271His/Asp2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568    
665121 Morlock GP AAC 2000 CAT/CGT21271His/Arg1999 SequencingWhole geneZ>800Proportion method37/601/0  High confidence details 
666122 Cheng SJ AAC 2000 CAT/CAG21371His/Glu USASequencingWhole geneZHRS>900Proportion method, BACTEC 46059/591/0    
667123 Scorpio A AAC 1997 TGC/CGC21472Cys/Arg1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0  High confidence details 
668124 Louw GE Int J Tuberc Lung Dis 2006 TGC/TAC21572Cys/Tyr2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568    
669125 Sekiguchi JI JCM 2007 TGC/TGG21672Cys/Trp2006JapanMulti-plex PCRWhole geneZ Proportion method, rapid broth method17/1381/0    
672128 Mestdagh M AAC 1999 ins G22174Frameshift1999United KingdomSequencingWhole geneZ BACTEC 460 23/622/0    
673129 Chan RCY JAC 2007 ATG/ACG22475Met/Thr1994-2004Hong KongPCR-SSCP , SequencingWhole geneZORH100ug/mlBACTEC MGIT 960 89/2501/0Asp94Gly (gyrA); Ser531Leu(rpoB); Met306Val(embB); Ser315Thr(katG)   
674130 Sreevatsan S AAC 1997 ACT/CCT22676Thr/Pro1996Diverse geographical locationsSequencingWhole geneZ BACTEC 46067/1181/0  High confidence details 
675131 Brown TJ JMedMicro 2000 ACT/ATT22776Thr/Ile2000United Kindom, TurkeySequencingWhole geneZHRP BACTEC 46013/188/0C2431T (rpoB)   
676132 Morlock GP AAC 2000 GGC/GAC23378Gly/Asp1999 SequencingWhole geneZ>800Proportion method37/601/0  High confidence details 
677133 Chan RCY JAC 2007 GCG/GGG23679Ala/Gly1994-2004Hong KongPCR-SSCP , SequencingWhole geneZ BACTEC MGIT 96025089    
679135 Sachais BS MolDiag 1998 TTC/GTC24180Phe/Val1993-1999USASequencingWhole geneZ BACTEC at pH 6.4398561/0    
680136 Brown TJ JMedMicro 2000 CAT/TAT Error? This makes Tyr not Asp.24482His/Asp2000TurkeySequencingWhole geneZHRP BACTEC 460 13/181/0A2386T (rpoB)   
681137 Cheng SJ AAC 2000 CAT/CGT24582His/Arg USASequencingWhole geneZHRES300Proportion method, BACTEC 46059/591/0  High confidence details 
682138 Rodrigues V de F AAC 2005 CAT/CTT24682His/Leu1998-2003BrazilSequencingWhole geneZ Proportion method5940    
684140 Mestdagh M AAC 1999 CTG/CGG25485Leu/Arg1999AzerbaijanSequencingWhole geneZ BACTEC 460 23/621/0  High confidence details 
685141 Scorpio A AAC 1997 CTG/CCG25485Leu/Pro1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/463/0  High confidence details 
686142 Lemaitre N AAC 1999 ACG/ATG26087Thr/Met1987FranceSequencingWhole geneZHRES1000-1500 19/351/0    
687143 Hou L Epi Infect 2000 TCG/TAG26388Ser/STOP1996-1998ChinaPCR-SSCPWhole geneZHRES>2000Proportion method, BACTEC 46035/651/0    
688144 Hannan MM JCM 2001 ATC/AGC26990Ile/Ser1996-1999USASequencingWhole geneZ BACTEC radiometric testing398831/0    
689145 Louw GE Int J Tuberc Lung Dis 2006 ATC/AGC26990Ile/Ser2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568    
690146 Sreevatsan S AAC 1997 TTC/CCC28094Phe/Pro1996Diverse geographical locationsSequencingWhole geneZ BACTEC 46067/1182/0T281C   
692148 Peridgao J MDR 2008 TAC/TAA28595Tyr/STOP2003PortugalSequencingWhole geneZHRS MGIT 96048/581/0    
693149 Lee KW J Korean Med Sci 2001 AAG/CAG28696Lys/Gln2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
694150 Marttila HJ AAC 1999 AAG/GAG28696Lys/Glu1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested   
695151 Scorpio A AAC 1997 AAG/ACG28796Lys/Thr1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
698154 Scorpio A AAC 1997 AAG/AAT28896Lys/Asn1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0  High confidence details 
700156 Cheng SJ AAC 2000 GGT/AGT28997Gly/Ser USASequencingWhole geneZHRES>900Proportion method, BACTEC 46059/592/0  High confidence details 
701157 Morlock GP AAC 2000 GGT/GAT29097Gly/Asp1999 SequencingWhole geneZ400Proportion method37/601/0  High confidence details 
702158 Hirano K TLD 1997 TAC/TAA29799Tyr/STOP1997ThailandSequencingWhole geneZHRSE>800Proportion method33/1681/0    
703159 Morlock GP AAC 2000 TAC/TAG29799Tyr/STOP1999 SequencingWhole geneZ>800Proportion method37/602/0  High confidence details 
706162 Marttila HJ AAC 1999 GCG/ACG304102Ala/Thr1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested   
707163 Marttila HJ AAC 1999 GCG/GTG305102Ala/Val1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/442/0not tested High confidence details 
709165 Mestdagh M AAC 1999 TAC/CAC307103Tyr/His1999CanadaSequencingWhole geneZ BACTEC 460 23/621/0    
711167 Lee KW J Korean Med Sci 2001 TAC/TCC308103Tyr/Ser2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/952/0  High confidence details 
712168 Lemaitre N AAC 1999 TAC/TGC308103Tyr/Cys1994FranceSequencingWhole geneZHRE1500  1/0    
713169 Marttila HJ AAC 1999 TAC/TAG309103Tyr/STOP1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested High confidence details 
714170 Morlock GP AAC 2000 TAC/TAA309103Tyr/STOP1999 SequencingWhole geneZ100Proportion method37/601/0    
715171 Scorpio A AAC 1997 del C312104Frameshift1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
716172 Hirano K TLD 1997 AGC/AGG312104Ser/Arg1997YemenSequencingWhole geneZHRSE>800Middlebrook 7H11 agar w/ pH of 6.033/1681/0  High confidence details 
717173 Louw GE Int J Tuberc Lung Dis 2006 GAA/AAA319107Gly/Lys2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568    
718174 Hirano K TLD 1997 ACG/CCG340114Thr/Pro1997YemenSequencingWhole geneZHR>800Middlebrook 7H11 agar w/ pH of 6.033/1681/0  High confidence details 
721177 Louw GE Int J Tuberc Lung Dis 2006 CTG/GTG346116Leu/Val2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568    
722178 Marttila HJ AAC 1999 CTG/CGG347116Leu/Arg1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested High confidence details 
723179 Hou L Epi Infect 2000 AAT/ACT353118Asn/Thr1996-1998ChinaPCR-SSCPWhole geneZHRS1000Proportion method, BACTEC 46035/651/0    
724180 Sreevatsan S AAC 1997 TGG/CGG355119Trp/Arg1996Diverse geographical locationsSequencingWhole geneZ BACTEC 46067/1181/0  High confidence details 
725181 Stavrum R PlosOne 2009 TGG/TGC357119Trp/CysPublished 2009IndiaSequencingWhole geneRSHE> 100 mg/LProportion method13/39(2/0)1) rpoB L511P; S531C; rpsL K42R; katG no mutation; inhA mutation present 2) rpoB L511P; S531C; rpsL K42R; katG mutation present; inhA mutation present   
726182 Lee KW J Korean Med Sci 2001 TGG/TGA357119Trp/STOP2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
727183 Portugal I AAC 2004 CTG/CCG359120Leu/Pro2000-2001PortugalSequencingWhole geneZ BACTEC MGIT 9605555  High confidence details 
728184 Sreevatsan S AAC 1997 CGG/CCG362121Arg/Pro1996Diverse geographical locationsSequencingWhole geneZ BACTEC 46067/1181/0  High confidence details 
731187 Marttila HJ AAC 1999 GTC/GAC374125Val/Asp1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested   
732188 Peridgao J MDR 2008 GTC/GGC374125Val/Gly2003PortugalSequencingWhole geneZHRS MGIT 96048/5819/0  High confidence details 
737193 Rodrigues V de F AAC 2005 GTC/GGC384128Val/Gly1998-2003BrazilSequencingWhole geneZ Proportion method and Pzase test5940  High confidence details 
741197 Hirano K TLD 1997 GTG/GGG389130Val/Gly1997CanadaSequencingWhole geneZHRSE>800Middlebrook 7H11 agar w/ pH of 6.033/1681/0  High confidence details 
746202 Hirano K TLD 1997 GGT/GAT395132Gly/Asp1997MyanmarSequencingWhole geneZ>800Proportion method33/1681/0  High confidence details 
747203 Scorpio A AAC 1997 GGT/AGT394132Gly/Ser1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/462/0  High confidence details 
750206 Marttila HJ AAC 1999 ATT/ACT398133Ile/Thr1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested   
751207 Morlock GP AAC 2000 ATT/AAT398133Ile/Asn1999 SequencingWhole geneZ800Proportion method37/601/0    
752208 Escalante P TuberLung Dis 1998 GCC/GTC401134Ala/Val1995-1996PeruSequencingWhole geneZHRP Proportion method401461/0katG, 315, AGC/ACC; rpoB, 531, TCG/TTG; High confidence details 
753209 Morlock GP AAC 2000 ACC/CCC403135Thr/Pro1999 SequencingWhole geneZ>800Proportion method37/601/0    
756212 Lee KW J Korean Med Sci 2001 GAT/TAT406136Asp/Tyr2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/952/0    
757213 Lee KW J Korean Med Sci 2001 GAT/AAT406136Asp/Asn2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
758214 Mestdagh M AAC 1999 GAT/CAT406136Asp/His1999ScotlandSequencingWhole geneZ BACTEC 460 23/621/0    
760216 Louw GE Int J Tuberc Lung Dis 2006 GAT/GGT407136Asp/Gly2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568    
762218 Scorpio A AAC 1997 CAT/CCT410137His/Pro1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
763219 Sreevatsan S AAC 1997 CAT/CGT410137His/Arg1996Diverse geographical locationsSequencingWhole geneZ BACTEC 46067/1182/0  High confidence details 
764220 Cheng SJ AAC 2000 TGT/TCT413138Cys/Ser South koreaSequencingWhole geneZ>500Proportion method, BACTEC 46059/591/0?    
765221 Scorpio A Nature Med 1996 TGT/TAT413138Cys/Tyr USA (Colorado)SequencingWhole geneMDR>500ug/mlPzase testing by Wayne's method399101/0  High confidence details 
767223 Cheng SJ AAC 2000 GTG/ATG415139Val/Met South koreaSequencingWhole geneZ>500Proportion method, BACTEC 46059/591/0?  High confidence details 
768224 Morlock GP AAC 2000 GTG/CTG415139Val/Leu1999 SequencingWhole geneZ100Proportion method37/601/0  High confidence details 
769225 Morlock GP AAC 2000 GTG/GGG416139Val/Gly1999 SequencingWhole geneZ>800Proportion method37/601/0  High confidence details 
770226 Sreevatsan S AAC 1997 GTG/GCG416139Val/Ala1996Diverse geographical locationsSequencingWhole geneZ BACTEC 46067/1181/0  High confidence details 
772228 Cheng SJ AAC 2000 CGC/AGC418140Arg/Ser  SequencingWhole geneZ Proportion method, BACTEC 46059/5920/0  High confidence details 
776232 Lee KW J Korean Med Sci 2001 CAG/TAG421141Gln/STOP2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
777233 Scorpio A Nature Med 1996 CAG/CCG422141Gln/Pro USASequencingWhole geneMDR>500ug/mlPzase testing by Wayne's methodinvitro1/0  High confidence details 
778234 Escalante P TuberLung Dis 1998 ACG/CCG424142Thr/Pro1995, 1996PeruSequencingWhole geneMDR Proportion method401461/0rpoB, 516, GAC/TAC High confidence details 
779235 Hirano K TLD 1997 ACG/GCG424142Thr/Ala1997MyanmarSequencingWhole geneZHRSE>800Middlebrook 7H11 agar w/ pH of 6.033/1681/0    
780236 Scorpio A AAC 1997 ACG/AAG425142Thr/Lys1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0  High confidence details 
781237 Scorpio A AAC 1997 ACG/ATG425142Thr/Met1992-1995 PCR-SSCPWhole geneZ>900ug/mlPzase testing by Wayne's method46/461/0    
783239 Lee KW J Korean Med Sci 2001 GCG/ACG436146Ala/Thr2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
785241 Hirano K TLD 1997 GCG/GTG437146Ala/Val1997IndiaSequencingWhole geneZRS>800Proportion method33/1681/0  High confidence details 
787243 Sekiguchi JI JCM 2007 CGC/AGC442148Arg/Ser2006PolandMulti-plex PCRWhole geneZ Proportion method, rapid broth method17/1381/0  High confidence details 
788244 Brown TJ JMedMicro 2000 C/A442148Arg/Ser2000TurkeySequencingWhole geneZHRP BACTEC 460 13/181/0C2431G(rpoB)   
793249 Morlock GP AAC 2000 ACC/AAC458153Thr/Asn1999 SequencingWhole geneZ800Proportion method37/601/0    
794250 Marttila HJ AAC 1999 AGG/GGG460154Arg/Gly1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/441/0not tested   
795251 Lemaitre N AAC 1999 GTG/GGG464155Val/Gly1987FranceSequencingWhole geneZHRE1500 19/351/0  High confidence details 
796252 Escalante P TuberLung Dis 1998 GTG/GCG464155Val/Ala1995, 1996PeruSequencingWhole geneZHRES Proportion method401461/0katG, 315, AGC/ACC; rpoB, 531, TCG/TTG; High confidence details 
799255 Louw GE Int J Tuberc Lung Dis 2006 CTG/CCG476159Leu/Pro2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568  High confidence details 
800256 Lee KW J Korean Med Sci 2001 CTG/CGG476159Leu/Arg2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0  High confidence details 
801257 Marttila HJ AAC 1999 ACA/CCA478160Thr/Pro1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/442/0not tested High confidence details 
803259 Marttila HJ AAC 1999 GCG/CCG481161Ala/Pro1994-1997RussiaSequencingWhole geneZ BACTEC 460 36/442/0not tested High confidence details 
804260 Chan RCY JAC 2007 GGT/GAT485162Gly/Asp1994-2004Hong KongPCR-SSCP , SequencingWhole geneZOREth100mg/LBACTEC MGIT 96089/2501/0Asp94Gly (gyrA); Ser531Leu(rpoB); Met306Val(embB) High confidence details 
806262 Cheng SJ AAC 2000 ACC/AAC503168Thr/Asn CanadaSequencingWhole geneZRO300Proportion method, BACTEC 46059/591/0    
807263 Mestdagh M AAC 1999 GCG/ACG511171Ala/Thr1999BangladeshSequencingWhole geneZ BACTEC 460 23/621/0    
808264 Sachais BS MolDiag 1998 GCG/CCG511171Ala/Pro1993-1999USASequencingWhole geneZ BACTEC at pH 6.4398561/0  High confidence details 
809265 Mestdagh M AAC 1999 GCG/GTG512171Ala/Val1999ScotlandSequencingWhole geneZ BACTEC 460 23/621/0  High confidence details 
810266 Rodrigues V de F AAC 2005 GCG/GAG512171Ala/Glu1998-2003BrazilSequencingWhole geneZ Proportion method5940  High confidence details 
812268 Hirano K TLD 1997 CTG/CCG515172Leu/Pro1997CanadaSequencingWhole geneZHRSE>800Proportion method33/1681/0  High confidence details 
813269 Mestdagh M AAC 1999 CTG/GCG514-515172Leu/Ala1999BelgiumSequencingWhole geneZ BACTEC 460 23/622/0    
815271 Sekiguchi JI JCM 2007 ATG/GTG523175Met/Val2006JapanMulti-plex PCRWhole geneZ Proportion method, rapid broth method17/1381/0    
817273 Louw GE Int J Tuberc Lung Dis 2006 AGC/CGC535179Ser/Arg2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568    
818274 Lee KW J Korean Med Sci 2001 GTC/TTC538180Val/Phe2001South koreaSequencingWhole geneZ PZase test with Wayne's method92/951/0    
819275 Louw GE Int J Tuberc Lung Dis 2006 GAG/GAT543181Glu/Asp2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568    
820276 Lemaitre N AAC 1999 TTG/TCG545182Leu/Ser1997FranceSequencingWhole geneZHRS500-2000ug/ml 19/351/0    
821277 Louw GE Int J Tuberc Lung Dis 2006 AGC/ACC554185Ser/Thr2001-2002South AfricaSequencingWhole geneZHRSEthK BACTEC MGIT 96011568  High confidence details 
822278 Chan RCY JAC 2007 AGC/ATC554185Ser/Ile1994-2004Hong KongPCR-SSCP , SequencingWhole geneZ BACTEC MGIT 96025089    

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