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ETHAMBUTOL [EMB]


Rv0340: Rv0340iniB: Rv0341iniA: Rv0342iniC: Rv0343embR: Rv1267cRv3124: Rv3124Rv3125c: Rv3125cRv3126: Rv3126Rv3264c: Rv3264cRv3266c: Rv3266cembC: Rv3793embA: Rv3794embB: Rv3795

Rv3795

More about Rv3795 on    TBDB.org

More about Rv3795 on    TubercuList

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Codons 1000 to 1049:2 Mutation Codons 950 to 999:1 Mutation Codons 700 to 749:1 Mutation Codons 650 to 699:1 Mutation Codons 600 to 649:1 Mutation Codons 450 to 499:10 Mutation Codons 400 to 449:20 Mutation Codons 350 to 399:37 Mutation Codons 300 to 349:36 Mutation Codons 250 to 299:18 Mutation Codons 200 to 249:5 Mutation Codons 100 to 149:1 Mutation
Select interval to show only those mutations included. Selected interval is marked with a red color.
IDSeqNoAdded byPrimary referencePolymorphismNucleotide positionCodon positionAmino acidTime periodOriginMolecular detection methodGene coverageResistance patternMICSusceptibility testing methodR/Total isolatesR/S isolates with mutationAdditional mutationsEditDeleteHigh confidence supportSelect
91552 Escalante P TuberLung Dis 1998 del A983 FrameshiftPublished 1998; isolates collected 1995-1996PeruSequencingERDREN.S.Proportion method401461/0None in region amplified (see Gene coverage).   
8641 Srivastava S CurrMicro 2006 GTC/GGG383128Val/GlyPublished 2006IndiaSequencingERDRE, EHR, HR, EH5ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
8652 Jain A IndJMedRes 2008 GCG/GGC662-663221Ala/Gly2002-2004IndiaSequencingERDREHRS>20ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
8663 Jain A IndJMedRes 2008 GCG/AGC673-674225Ala/Ser2002-2004IndiaSequencingERDREHRS>20ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
8674 Jain A IndJMedRes 2008 GTG/GGC680-681227Val/Gly2002-2004IndiaSequencingERDREHRS>20ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
8685 Srivastava S CurrMicro 2006 CTC/CCC716239Leu/ProPublished 2006IndiaSequencingERDRE, EHR, HR, EH256ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
8696 Srivastava S CurrMicro 2006 GAC/CAC718240Asp/HisPublished 2006IndiaSequencingERDRE, EHR, HR, EH4ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
8707 Srivastava S JMM 2009 CGT/TGG769-771257Arg/TrpPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embC V287F, Y309N; embR A176V, R230W, I369T   
8718 Jain A IndJMedRes 2008 GCG/GTG812271Ala/Val2002-2004IndiaSequencingERDREHRS>20ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
8729 Jain A IndJMedRes 2008 AGC/TGC814272Ser/Cys2002-2004IndiaSequencingERDREHRS>20ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
87310 Jain A IndJMedRes 2008 AGC/ATT815-816272Ser/Ile2002-2004IndiaSequencingERDREHRS>20ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
87411 Wu X Chinese J of Antibiotics 2002 CGC/CCC821274Arg/Pro             
87512 Jain A IndJMedRes 2008 GCG/CCG841281Ala/Pro2002-2004IndiaSequencingERDREHRS>20ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
87613 Jain A IndJMedRes 2008 TTT/CTG841-843281Phe/Leu2002-2004IndiaSequencingERDREHRS>20ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
87714 Srivastava S JMM 2009 GTG/GGG845282Val/GlyPublished 2009IndiaSequencingWhole geneEHR12ug/mlProportion method, E-Test44/441/0None in region embB, embC or embR'   
87815 Jain A IndJMedRes 2008 GTG/CTG844282Val/Leu2002-2004IndiaSequencingERDREHRS>20ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
87916 Sreevatsan S AAC 1997 TTC/TTA855285Phe/LeuPublished 1997USA, Mexico, Europe, Yemen, the Philippines, Japan, IndiaPCR-SSCP, SequencingWhole geneEN.S.BACTEC 460, agar diffusion method69/991/0    
88017 Jain A IndJMedRes 2008 TTT/TGC860-861287Phe/Cys2002-2004IndiaSequencingERDREHRS>20ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
88118 Jain A IndJMedRes 2008 TTT/GTG859-861287Phe/Val2002-2004IndiaSequencingERDREHRS>20ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
88219 Jain A IndJMedRes 2008 ATT/AAC878-879293Ile/Asn2002-2004IndiaSequencingERDREHRS>20ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
88320 Jain A IndJMedRes 2008 GGC/AGC880294Gly/Ser2002-2004IndiaSequencingERDREHRS>20ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1. High confidence details 
88421 Srivastava S JMM 2009 AAT/AAA888296Asn/LysPublished 2009IndiaSequencingWhole geneEHR16ug/mlProportion method, E-Test44/441/0embB E368D, G406S; embC I297T   
88522 Ramaswamy SV AAC 2000 TCG/GCG889297Ser/AlaPublished 2000USA, RussiaSequencingWhole geneE10-50ug/mlBACTEC 460, agar diffusion method75/1081/0    
88623 Plinke C AAC 2006 TCG/TTG890297Ser/Leu2001GermanySequencingERDRE + INH + RIF N.S.Proportion method, BACTEC 460101/1591/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
88724 Srivastava S CurrMicro 2006 GAC/GAA897299Asp/GluPublished 2006IndiaSequencingERDRE, EHR, HR, EH2-6ug/mlProportion method, E-Test23/234/0Out of 4 isolates, 2 were WT in all other loci analyzed except for a synonymous mutation (GCA/GCC) at embB259. These isolates had MIC=4-6ug/ml. Both other isolates contained the embB mutation Glu378Ala (GAA/GCG); one of them was also mutated at embB Pro44   
88825 Sreevatsan S AAC 1997 ATG/CTG916306Met/LeuPublished 1997USA, Mexico, Europe, Yemen, the Philippines, Japan, IndiaPCR-SSCP, SequencingWhole geneE40ug/mlBACTEC 460, agar diffusion method69/991/0  High confidence details 
88926 Lee HY YonseiMedJ 2002 ATG/TTG916306Met/LeuPublished 2002South KoreaSequencingWhole geneE, 2ug/mlProportion method21/261/0None in region amplified (see Gene coverage).   
89027 Sreevatsan S AAC 1997 ATG/GTG916306Met/ValPublished 1997USA, Mexico, Europe, Yemen, the Philippines, Japan, IndiaPCR-SSCP, SequencingWhole geneE40ug/mlBACTEC 460, agar diffusion method69/9912/0  High confidence details 
89128 Sreevatsan S AAC 1997 ATG/ATA918306Met/IlePublished 1997USA, Mexico, Europe, Yemen, the Philippines, Japan, IndiaPCR-SSCP, SequencingWhole geneE20ug/mlBACTEC 460, agar diffusion method69/9911/0  High confidence details 
89229 Sreevatsan S AAC 1997 ATG/ATT918306Met/IlePublished 1997USA, Mexico, Europe, Yemen, the Philippines, Japan, IndiaPCR-SSCP, SequencingWhole geneE20ug/mlBACTEC 460, agar diffusion method69/992/0  High confidence details 
89330 Sreevatsan S AAC 1997 ATG/ATC918306Met/IlePublished 1997USA, Mexico, Europe, Yemen, the Philippines, Japan, IndiaPCR-SSCP, SequencingWhole geneE20ug/mlBACTEC 460, agar diffusion method69/993/0  High confidence details 
89431 Lee HY YonseiMedJ 2002 ATG/ACG917-918306Met/ThrPublished 2002South KoreaSequencingERDRE2ug/mlProportion method21/261/0None in region amplified (see Gene coverage).   
89532 Srivastava S JMM 2009 GTG/GGC926-927309Val/GlyPublished 2009IndiaSequencingWhole geneEHR128ug/mlProportion method, E-Test44/441/0embB M306V, A310R, D311R, V369A, P375A, F398Y, P461S; embC T270I; embR G240R   
89633 Srivastava S JMM 2009 GCG/CGT928-930310Ala/ArgPublished 2009IndiaSequencingWhole geneEHR128ug/mlProportion method, E-Test44/441/0embB M306V, V309G, D311R, V369A, P375A, F398Y, P461S; embC T270I; embR G240R   
89734 Srivastava S JMM 2009 GAC/CGT931-932311Asp/ArgPublished 2009IndiaSequencingWhole geneEHR128ug/mlProportion method, E-Test44/441/0embB M306V, V309G, A310R, V369A, P375A, F398Y, P461S; embC T270I; embR G240R   
89835 Srivastava S CurrMicro 2006 GAC/CAC931311Asp/HisPublished 2006IndiaSequencingERDRE, EHR, HR, EH12ug/mlProportion method, E-Test23/231/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
89936 Srivastava S JMM 2009 CAT/CGT935312His/ArgPublished 2009IndiaSequencingWhole geneEHR96ug/mlProportion method, E-Test44/441/0embB S317T, A356F, L359I, R367P; embC G288V, M310K, Y327N   
90037 Lee HY YonseiMedJ 2002 GGC/GCG941314Gly/AlaPublished 2002South KoreaSequencingERDRE4ug/mlProportion method21/261/0Tyr322Cys on embB.   
90138 Tracevska T ResMicro 2004 GGC/GAG941-942314Gly/GluPublished 2004; isolates collected in 2001-2002LatviaSequencingERDREHRSN.S.BACTEC radiorespiratory method (7.5ug/ml EMB), and absolute concentration method on L-J medium (cutoff 2.0ug/ml EMB)33/661/0None in region amplified (see Gene coverage).   
90239 Srivastava S JMM 2009 TAT/CTG943-945315Tyr/LeuPublished 2009IndiaSequencingWhole geneEHR256ug/mlProportion method, E-Test44/441/0embB L239P, N318S, V377G, E378A, Y384N, N400K, V452L   
90340 Srivastava S JMM 2009 AGC/ACC950317Ser/ThrPublished 2009IndiaSequencingWhole geneEHR96ug/mlProportion method, E-Test44/441/0embB H312R, A356F, L359I, R367P; embC G288V, M310K, Y327N   
90441 Srivastava S JMM 2009 AAC/CAT352318Asn/HisPublished 2009IndiaSequencingWhole geneEHR16ug/mlProportion method, E-Test44/441/0embC T270I   
90542 Srivastava S JMM 2009 AAC/AGC953318Asn/SerPublished 2009IndiaSequencingWhole geneEHR256ug/mlProportion method, E-Test44/441/0embB L239P, Y315L, V377G, E378A, Y384N, N400K, V452L   
90643 Srivastava S JMM 2009 AAC/AAA954318Asn/LysPublished 2009IndiaSequencingWhole geneEHR32ug/mlProportion method, E-Test44/441/0embB M306V, N368A, S380R, P397Q, G459A, R460C; embR T32P, D53H   
90744 Sugawara I Jpn J Infect Dis 2005 TAT/GAT955319Tyr/Cys             
90845 Chan RCY JAC 2007 TAT/AAT955319Tyr/Asn             
90946 Sugawara I Jpn J Infect Dis 2005 TAT/TGT956319Tyr/Cys             
91047 Plinke C AAC 2006 TAT/TCT956319Tyr/Ser2001GermanySequencingERDREHRN.S.Proportion method, BACTEC 460101/1591/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
91148 Lee HY YonseiMedJ 2002 TAT/TGT965322Tyr/CysPublished 2002South KoreaSequencingERDRE4ug/mlProportion method21/261/0Ala314Gly on embB.   
91249 Ramaswamy SV AAC 2000 GAT/TAT982328Asp/TyrPublished 2000USA, RussiaSequencingWhole geneE30ug/mlBACTEC 460, agar diffusion method75/1081/0Ala201Thr in embA, Tyr334His in embB.   
91350 Ramaswamy SV AAC 2000 GAT/GGT983328Asp/GlyPublished 2000USA, RussiaSequencingWhole geneE10-50ug/mlBACTEC 460, agar diffusion method75/1081/0    
91451 Plinke C AAC 2006 GAT/GTG983-984328Asp/Val2001GermanySequencingERDREHRN.S.Proportion method, BACTEC 460101/1591/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
91653 Sreevatsan S AAC 1997 TTC/GTC988330Phe/ValPublished 1997USA, Mexico, Europe, Yemen, the Philippines, Japan, IndiaPCR-SSCP, SequencingWhole geneE40ug/mlBACTEC 460, agar diffusion method69/991/0    
91754 Srivastava S JMM 2009 GGC/CGT991-993331Gly/ArgPublished 2009IndiaSequencingWhole geneER16ug/mlProportion method, E-Test44/441/0embB V360M, G374V, G401S; embC I297T; embR D223E   
91855 Lee HY YonseiMedJ 2002 GAT/TAT991331Asp/TyrPublished 2002KoreaSequencingERDRE4ug/mlProportion method21/261/0None in region amplified (see Gene coverage).   
91956 Plinke C AAC 2006 TGG/CTG994-995332Trp/Leu2001GermanySequencingERDREHRN.S.Proportion method, BACTEC 460101/1591/0None in region amplified (see Gene coverage). R/Tot and R/S calculated from Table 1.   
92057 Sugawara I Jpn J Infect Dis 2005 TAT/CAT997333Tyr/His             
92158 Ramaswamy SV AAC 2000 TAC/CAC1000334Tyr/HisPublished 2000USA, RussiaSequencingWhole geneE30ug/mlBACTEC 460, agar diffusion method75/1081/0Ala201Thr in embA, Asp328Tyr in embB.   
92259 Escalante P TuberLung Dis 1998 AGT/ACT1040347Ser/ThrPublished 1998; isolates collected 1995-1996PeruSequencingERDREN.S.Proportion method401461/0None in region amplified (see Gene coverage).   
92360 Srivastava S JMM 2009 AGT/ATT1040347Ser/IlePublished 2009IndiaSequencingWhole geneEHR4ug/mlProportion method, E-Test44/441/0embB E368D, R460L; embC I297T; embR R230W, I396T   
92461 Srivastava S JMM 2009 GCG/TTT1066-1068356Ala/PhePublished 2009IndiaSequencingWhole geneEHR96ug/mlProportion method, E-Test44/441/0embB H312R, S317T, L359I, R367P; embC G288V, M310K, Y327N   
92562 Srivastava S JMM 2009 GCG/AGC1066-1068356Ala/SerPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embB D299E, P371R, E378K; embR R230W, L292M, L303E   
92663 Srivastava S JMM 2009 GCG/GTG1067356Ala/ValPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embB M306L, S366P, W395R, A434G, V435G, V436G, T437A; embC T270I   
92764 Srivastava S JMM 2009 GCG/AGC1069-1071357Ala/SerPublished 2009IndiaSequencingWhole geneEHR2ug/mlProportion method, E-Test44/441/0embB A379T; embC V287F, Y309N; embR L320V S326N, V350G, H351Q, R356G, I369T   
92865 Srivastava S JMM 2009 GCG/GTG1070357Ala/ValPublished 2009IndiaSequencingWhole geneEHR8ug/mlProportion method, E-Test44/441/0embB A356F, L359I, E378A, A379D, Y384N, A388G, N399D, G406P; embC A247P, T270I, I297T   
92966 Srivastava S JMM 2009 GGC/GTG1073-1074358Gly/ValPublished 2009IndiaSequencingWhole geneEHR3ug/mlProportion method, E-Test44/441/0embB E368Q, S380D, P397T, G406D, G448V; embC I287L, W326R   
93067 Srivastava S JMM 2009 CTG/ATT1075-1077359Leu/IlePublished 2009IndiaSequencingWhole geneEHR96ug/mlProportion method, E-Test44/441/0embB H312R, S317T, A356F, R367P; embC G288V, M310K, Y327N   
93168 Srivastava S JMM 2009 GTG/ATG1078360Val/MetPublished 2009IndiaSequencingWhole geneER16ug/mlProportion method, E-Test44/441/0embB G331R, G374V, G401S; embC I297T; embR D223E   
93269 Srivastava S JMM 2009 AGC/CCG1096366Ser/ProPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embB M306L, A356V, W395R, A434G, V435G, V436G, T437A; embC T270I   
93370 Srivastava S JMM 2009 CGT/CCG1100-1101367Arg/ProPublished 2009IndiaSequencingWhole geneEHR96ug/mlProportion method, E-Test44/441/0embB H312R, S317T, A356F, L359I; embC G288V, M310K, Y327N   
93471 Srivastava S JMM 2009 GAA/CAG1102-1104368Glu/GlnPublished 2009IndiaSequencingWhole geneEHR3ug/mlProportion method, E-Test44/441/0embB G358V, S380D, P397T, G406D, G448V; embC I287L, W326R   
93572 Srivastava S JMM 2009 GAA/GAT1104368Glu/AspPublished 2009IndiaSequencingWhole geneEHR4ug/mlProportion method, E-Test44/441/0embB S347I, R460L; embC I297T; embR R230W, I396T   
93673 Srivastava S CurrMicro 2006 GAA/GCG1103-1104368Glu/AlaPublished 2006IndiaSequencingERDRE, EHR, HR, EH32ug/mlProportion method23/231/0Met306Val, Ser380Arg, and Pro397Gln on embB.   
93774 Srivastava S JMM 2009 GTG/CTG1105369Val/LeuPublished 2009IndiaSequencingWhole geneEHR12ug/mlProportion method, E-Test44/441/0embB M306I; embC L251R, A354G, T270I   
93875 Srivastava S JMM 2009 GTG/GCG1106369Val/AlaPublished 2009IndiaSequencingWhole geneEHR128ug/mlProportion method, E-Test44/441/0embB M306V, V309G, A310R, D311R, P375A, F398Y, P461S; embC T270I; embR G240R   
176 Srivastava S JMM 2009 CTG/CGT1109-1110370Leu/ArgPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embB V377M, E378A, F398H, N399H, E405P, G406A   
277 Srivastava S JMM 2009 CCG/CGT1112-1113371Pro/ArgPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embB D299E, A356S, E378K; embR R230W, L292M, L303E   
378 Srivastava S JMM 2009 GGC/GTG1121-1122374Gly/ValPublished 2009IndiaSequencingWhole geneEH4ug/mlProportion method, E-Test44/441/0embC W395C, N400P; embC G288W, V303G; embR A187V, R230W, I369T   
479 Srivastava S JMM 2009 CCG/GCG1123-1124375Pro/AlaPublished 2009IndiaSequencingWhole geneEHR128ug/mlProportion method, E-Test44/441/0embB M306V, V309G, A310R, D311R, V369A, F398Y, P461S; embC T270I; embR G240R   
580 Srivastava S JMM 2009 GTG/ATG1129377Val/MetPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embB L370R, E378A, F398H, N399H, E405P, G406A   
681 Srivastava S JMM 2009 GTG/GGC1130-1131377Val/GlyPublished 2009IndiaSequencingWhole geneEHR256ug/mlProportion method, E-Test44/441/0embB L239P, Y315L, N318S, E378A, Y384N, N400K, V452L   
782 Srivastava S JMM 2009 GAA/AAA1132378Glu/LysPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embB D299E, A356S, P371R; embR R230W, L292M, L303E   
883 Srivastava S CurrMicro 2006 GAA/GCG1103-1104378Glu/AlaPublished 2006IndiaSequencingERDRE, EHR, HR, EH2ug/mlProportion method23/232/0Both of these isolates were mutated at embB Asp299Glu. One was also mutated at embB Pro446His and Ile465Asp, as well as embC Thr270Ile and 254 Synonymous (GCC/GCG). The other isolate was mutated at embBArg469Pro and Arg 471Pro. R/Tot and R/S calculated fr   
984 Srivastava S JMM 2009 GCG/ACC1135-1137379Ala/ThrPublished 2009IndiaSequencingWhole geneEHR2ug/mlProportion method, E-Test44/441/0embB A357S; embC V287F, Y309N; embR L320V S326N, V350G, H351Q, R356G, I369T   
1085 Srivastava S JMM 2009 GCG/GAT1136-1137379Ala/AspPublished 2009IndiaSequencingWhole geneEHR8ug/mlProportion method, E-Test44/441/0embB A356F, A357V, L359I, E378A, Y384N, A388G, N399D, G406P; embC A247P, T270I, I297T   
1186 Srivastava S CurrMicro 2006 AGC/CGT1138-1140380Ser/ArgPublished 2006IndiaSequencingERDRE, EHR, HR, EH 32ug/mlProportion method23/231/0Met306Val, Glu368Ala, and Pro397Gln on embB. R/Tot and R/S calculated from Table 1.   
1287 Srivastava S JMM 2009 AGC/AAC1139380Ser/AspPublished 2009IndiaSequencingWhole geneEHR3ug/mlProportion method, E-Test44/441/0embB G358V, E368Q, P397T, G406D, G448V; embC I287L, W326R   
1388 Srivastava S JMM 2009 TAT/AAC1150-1152384Tyr/AsnPublished 2009IndiaSequencingWhole geneEHR256ug/mlProportion method, E-Test44/441/0embB L239P, Y315L, N318S, V377G, E378A, N400K, V452L   
1489 Srivastava S JMM 2009 GCG/GGC1163-1164388Ala/GlyPublished 2009IndiaSequencingWhole geneEHR8ug/mlProportion method, E-Test44/441/0embB A356F, A357V, L359I, E378A, A379D, Y384N, N399D, G406P; embC A247P, T270I, I297T   
1590 Srivastava S JMM 2009 TGG/CGT1183-1185395Trp/ArgPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embB M306L, A356V, S366P, A434G, V435G, V436G, T437A; embC T270I   
1691 Srivastava S JMM 2009 TGG/TGC1185395Trp/CysPublished 2009IndiaSequencingWhole geneEH4ug/mlProportion method, E-Test44/441/0embC G374V, N400P; embC G288W, V303G; embR A187V, R230W, I369T   
1792 Srivastava S JMM 2009 CCG/ACC1189-1190397Pro/ThrPublished 2009IndiaSequencingWhole geneEHR3ug/mlProportion method, E-Test44/441/0embB G358V, E368Q, S380D, G406D, G448V; embC I287L, W326R   
1893 Srivastava S CurrMicro 2006 CCG/CAG1190397Pro/GlnPublished 2006IndiaSequencingERDRE, EHR, HR, EH 32ug/mlProportion method23/231/0Met306Val, Glu368Ala, and Ser380Arg on embB. R/Tot and R/S calculated from Table 1.   
1994 Srivastava S JMM 2009 TTT/CAT1192-1193398Phe/HisPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embB L370R, V377M, E378A, N399H, E405P, G406A   
2095 Srivastava S JMM 2009 TTT/TAT1193398Phe/TyrPublished 2009IndiaSequencingWhole geneEHR128ug/mlProportion method, E-Test44/441/0embB M306V, V309G, A310R, D311R, V369A, P375A, P461S; embC T270I; embR G240R   
2196 Srivastava S JMM 2009 TTT/GAT1195-1196399Asn/AspPublished 2009IndiaSequencingWhole geneEHR8ug/mlProportion method, E-Test44/441/0embB A356F, A357V, L359I, E378A, A379D, Y384N, A388G, G406P; embC A247P, T270I, I297T   
2297 Srivastava S JMM 2009 TTT/CAT1195-1196399Asn/HisPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embB L370R, V377M, E378A, F398H, E405P, G406A   
2398 Srivastava S JMM 2009 AAC/CCG1198-1200400Asn/ProPublished 2009IndiaSequencingWhole geneEH4ug/mlProportion method, E-Test44/441/0embC G374V, W395C; embC G288W, V303G; embR A187V, R230W, I369T   
2499 Srivastava S JMM 2009 AAC/AAA1200400Asn/LysPublished 2009IndiaSequencingWhole geneEHR256ug/mlProportion method, E-Test44/441/0embB L239P, Y315L, N318S, E378A, Y384N, V452L   
25100 Srivastava S JMM 2009 ACG/ACA1203401Gly/SerPublished 2009IndiaSequencingWhole geneER16ug/mlProportion method, E-Test44/441/0embB G331R, G374V, G374V; embC I297T; embR D223E   
26101 Srivastava S JMM 2009 GAA/CCG1213-1214405Glu/ProPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embB L370R, V377M, E378A, F398H, N399H, G406A   
27102 Srivastava S JMM 2009 GGC/CCG1216406Gly/ProPublished 2009IndiaSequencingWhole geneEHR8ug/mlProportion method, E-Test44/441/0embB A356F, A357V, L359I, E378A, A379D, Y384N, A388G, N399D; embC A247P, T270I, I297T   
28103 Ramaswamy SV AAC 2000 GGC/AGC1216406Gly/SerPublished 2000USA, RussiaSequencingWhole geneE30ug/mlBACTEC 460, agar diffusion method75/1081/0-43 CG deletion in embA. High confidence details 
29104 Ramaswamy SV AAC 2000 GGC/TGC1216406Gly/CysPublished 2000USA, RussiaSequencingWhole geneE30-50ug/mlBACTEC 460, agar diffusion method75/1082/0    
30105 Srivastava S JMM 2009 GGC/GAT1217406Gly/AspPublished 2009IndiaSequencingWhole geneEHR3ug/mlProportion method, E-Test44/441/0embB G358V, E368Q, S380D, P397T, G448V; embC I287L, W326R   
31106 Ramaswamy SV AAC 2000 GGC/GAC1217406Gly/AspPublished 2000USA, RussiaSequencingWhole geneE40ug/mlBACTEC 460, agar diffusion method75/1081/0Asp4Asn in embA High confidence details 
32107 Ramaswamy SV AAC 2000 GGC/GCC1217406Gly/AlaPublished 2000USA, RussiaSequencingWhole geneE20ug/mlBACTEC 460, agar diffusion method75/1082/0In one of the isolates, -11 C/A in embA and Met306Ile in embB.   
33108 Srivastava S CurrMicro 2006 GGC/GCG1190406Gly/AlaPublished 2006IndiaSequencingERDRE, EHR, HR, EH 32ug/mlProportion method23/231/0Met306Val, Glu368Ala, and Ser380Arg on embB. R/Tot and R/S calculated from Table 1.   
34109 Lee AS AAC 2004 ATG/ATA1269423Met/IlePublished 2004SingaporeSequencingWhole geneEIN.S.BACTEC 46025/451/0None in region amplified (see Gene coverage). High confidence details 
35110 Srivastava S JMM 2009 CCG/CTG1289430Pro/LeuPublished 2009IndiaSequencingWhole geneEHR2ug/mlProportion method, E-Test44/441/0embB G406D, A431T; embC I297T   
36111 Srivastava S JMM 2009 GCG/ACC1291-1293431Ala/ThrPublished 2009IndiaSequencingWhole geneEHR2ug/mlProportion method, E-Test44/441/0embB G406D,P430L; embC I297T   
37112 Srivastava S JMM 2009 GCG/GGC1301-1302434Arg/GlyPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embB M306L, A356V, S366P, W395R, V435G, V436G, T437A; embC T270I   
38113 Srivastava S JMM 2009 GTG/GGC1304-1305435Val/GlyPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embB M306L, A356V, S366P, W395R, A434G, V436G, T437A; embC T270I   
39114 Srivastava S JMM 2009 GTG/GGC1307-1308436Val/GlyPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embB M306L, A356V, S366P, W395R, A434G, V435G, T437A; embC T270I   
40115 Srivastava S JMM 2009 ACC/GCG1309-1311437Thr/AlaPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embB M306L, A356V, S366P, W395R, A434G, V435G, V436G; embC T270I   
41116 Srivastava S CurrMicro 2006 CCG/CAT1337-1338446Pro/HisPublished 2006IndiaSequencingERDRE, EHR, HR, EH2ug/mlProportion method, E-Test23/231/0Asp299Glu, Glu378Ala, and Ile465Asp in embB; Thr270Ile and 254 Synonymous (GCC/GCG) in embC. R/T and R/S calculated from Table 1.   
42117 Srivastava S JMM 2009 GGC/GTG1343-1344448Gly/ValPublished 2009IndiaSequencingWhole geneEHR3ug/mlProportion method, E-Test44/441/0embB G358V, E368Q, S380D, P397T, G406D; embC I287L, W326R   
43118 Srivastava S JMM 2009 GTG/CTG1354452Val/LeuPublished 2009IndiaSequencingWhole geneEHR256ug/mlProportion method, E-Test44/441/0embB L239P, Y315L, N318S, E378A, Y384N, N400K   
44119 Srivastava S JMM 2009 GGC/GCG1376-1377459Gly/AlaPublished 2009IndiaSequencingWhole geneEHR32ug/mlProportion method, E-Test44/441/0embB M306V, N318K, N368A, S380R, P397Q, R460C; embR T32P, D53H   
45120 Srivastava S JMM 2009 CGT/TGC1378-1380460Arg/CysPublished 2009IndiaSequencingWhole geneEHR6ug/mlProportion method, E-Test44/441/0embB E368A, S380R, P397Q; embC A244T, G288W, V303G embR L172R   
46121 Srivastava S JMM 2009 CGT/CTG1379-1380460Arg/LeuPublished 2009IndiaSequencingWhole geneEHR4ug/mlProportion method, E-Test44/441/0embB S347I, E368D; embC I297T; embR R230W, I396T   
47122 Srivastava S JMM 2009 CCG/AGC1381-1383461Pro/SerPublished 2009IndiaSequencingWhole geneEHR128ug/mlProportion method, E-Test44/441/0embB M306V, V309G, A310R, D311R, V369A, P375A, F398Y; embC T270I; embR G240R   
48123 Srivastava S CurrMicro 2006 ATT/GAT1393-1394465Ile/AspPublished 2006IndiaSequencingERDRE, EHR, HR, EH2ug/mlProportion method, E-Test23/231/0Asp299Glu, Glu378Ala, and Pro446His in embB; Thr270Ile and 254 Synonymous (GCC/GCG) in embC. R/T and R/S calculated from Table 1.   
49124 Srivastava S CurrMicro 2006 CGT/CCG1406-1407469Arg/ProPublished 2006IndiaSequencingERDRE, EHR, HR, EH2ug/mlProportion method, E-Test23/231/0Asp299Glu, Glu378Ala, and Arg471Pro in embB. R/T and R/S calculated from Table 1.   
50125 Srivastava S CurrMicro 2006 CGT/CCG1412-1413471Arg/ProPublished 2006IndiaSequencingERDRE, EHR, HR, EH2ug/mlProportion method, E-Test23/231/0Asp299Glu, Glu378Ala, and Arg469Pro in embB. R/T and R/S calculated from Table 1.   
51126 Ramaswamy SV AAC 2000 CAG/CGG1490497Gln/ArgPublished 2000USA, RussiaSequencingWhole geneE30-50ug/mlBACTEC 460, agar diffusion method75/1083/0In one of the isolates: -12 C/T in embA, Ser501Trp in iniA. High confidence details 
52127 Ramaswamy SV AAC 2000 CAG/AAG1490497Gln/LysPublished 2000USA, RussiaSequencingWhole geneE30-50ug/mlBACTEC 460, agar diffusion method75/1082/0-12 C/T in embA at MIC=30ug/ml; -89 C/T in iniB at MIC>50ug/ml.   
53128 Sreevatsan S AAC 1997 ACC/ATC1889630Thr/IlePublished 1997USA, Mexico, Europe, Yemen, the Philippines, Japan, IndiaPCR-SSCP, SequencingWhole geneE>40ug/mlBACTEC 460, agar diffusion method69/992/0    
54129 Lee AS AAC 2004 GCG/ACG1975659Ala/ThrPublished 2004SingaporeSequencingWhole geneESN.S.BACTEC 46025/450/1None in region amplified (see Gene coverage).   
55130 Ramaswamy SV AAC 2000 GGC/GAC2234745Gly/AspPublished 2000USA, RussiaSequencingWhole geneE40ug/mlBACTEC 460, agar diffusion method75/1081/0Gly308Arg in iniA High confidence details 
56131 Ramaswamy SV AAC 2000 GAC/GCC2876959Asp/AlaPublished 2000USA, RussiaSequencingWhole geneE10-50ug/mlBACTEC 460, agar diffusion method75/1081/0    
57132 Ramaswamy SV AAC 2000 ATG/AGG29991000Met/ArgPublished 2000USA, RussiaSequencingWhole geneE10-50ug/mlBACTEC 460, agar diffusion method75/1081/0    
58133 Ramaswamy SV AAC 2000 GAC/AAC30701024Asp/AsnPublished 2000USA, RussiaSequencingWhole geneE10-50ug/mlBACTEC 460, agar diffusion method75/1081/0    

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