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AMINOGLYCOSIDES [AMI] (KANAMYCIN/CAPREOMYCIN/AMIKACIN/VIOMYCIN)


rrs: MTB000019tlyA: Rv1694

MTB000019

More about MTB000019 on    TBDB.org

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Codons 1450 to 1499:1 Mutation Codons 1400 to 1449:5 Mutation
Select interval to show only those mutations included. Selected interval is marked with a red color.
IDSeqNoAdded byPrimary referencePolymorphismNucleotide positionCodon positionAmino acidTime periodOriginMolecular detection methodGene coverageResistance patternMICSusceptibility testing methodR/Total isolatesR/S isolates with mutationAdditional mutationsEditDeleteHigh confidence supportSelect
2172 Sander P MolMicro 1996 A/G1401 rRNA genePublished 1996N.S.SequencingN.SKamiN.S.N.S.8/88/0none   
2183 Suzuki Y JCM 1998 C/T1402 rRNA genePublished 1998JapanSequencing300 bp containing the 3' one-fifth of the rrs geneKK >100ug/mlProportion method43/1181/0None found in gene analyzed.   
2194 Suzuki Y JCM 1998 C/A1402 rRNA genePublished 1998JapanSequencing300 bp containing the 3' one-fifth of the rrs geneKK >100ug/mlProportion method43/1182/0Both isolates also mutated at rrs G1484T.   
2205 Taniguchi H JB 1997 A/G1408 rRNA genePublished 1997JapanSequencingnt 431 to the 3' endRSEKVioK >200ug/mlN.S.399133/0Lys43Arg mutation in S12 protein in one isolate; Lys88Gln mutation in S12 protein in second isolate.   
2216 Suzuki Y JCM 1998 G/T1484 rRNA genePublished 1998JapanSequencing300 bp containing the 3' one-fifth of the rrs geneKK >100ug/mlProportion method43/1182/0Both isolates also mutated at rrs C1402A.   
11981 Maus CE AAC 2005 Aug A/G1401 rRNA genePublished 2005USASequencingWhole geneKAmiCapK >80ug/ml, Ami >64ug/ml, CAP 20-80ug/mlN.S.16/1611/09 isolates had no additional mutaitons; one had a mutation at rrs A514C; and one had a mutation at rrs A514C and T1239C.   

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