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STREPTOMYCIN [SM]


: rrs: MTB000019rpsL: Rv0682gidB: Rv3919c

MTB000019

More about MTB000019 on    TBDB.org

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Select interval to show only those mutations included. Selected interval is marked with a red color.
IDAdded byCountryTime periodSymbolGene IDMutationNo. of isolates testedNo. of isolates w/ mutationPercent tested w/ mutation Molecular detection method - gene coverageDST method - resistance pattern among R isolatesCommentsEditDeleteSelect
TotalRSRSRS
73 Poland2000rrsMTB000019491 (C/T)1038815000.00%0.00%Sequencing.Hot spot in rpsL and 530 and 912 loop of rrsBACTEC 460 and proportion method.N.S.    
74 Poland2000rrsMTB000019512 (C/T)1038815000.00%0.00%Sequencing.Hot spot in rpsL and 530 and 912 loop of rrsBACTEC 460 and proportion method.N.S.    
77 Poland2000rrsMTB000019516 (C/T)1038815000.00%0.00%Sequencing.Hot spot in rpsL and 530 and 912 loop of rrsBACTEC 460 and proportion method.N.S.    
270 IndiaN.S.rrsMTB000019491 (C/T)694920N/AN/AN/AN/ARFLP and sequencing.360 bp fragment of rpsLResistance ratio method and Absolute concentration method.N.S    
271 IndiaN.S.rrsMTB000019512 (C/T)694920N/AN/AN/AN/ARFLP and sequencing.360 bp fragment of rpsLResistance ratio method and Absolute concentration method.N.S    
274 IndiaN.S.rrsMTB000019516 (C/T)694920N/AN/AN/AN/ARFLP and sequencing.360 bp fragment of rpsLResistance ratio method and Absolute concentration method.N.S    
279 Germany, Sierra Leone1997rrsMTB000019491 (C/T)635013204.00%0.00%Sequencing.Hot spot in rpsL and 530 and 912 loop of rrsProportion method.About half of the isolates MDR    
280 Germany, Sierra Leone1997rrsMTB000019512 (C/T)635013000.00%0.00%Sequencing.Hot spot in rpsL and 530 and 912 loop of rrsProportion method.About half of the isolates MDR    
283 Germany, Sierra Leone1997rrsMTB000019516 (C/T)635013102.00%0.00%Sequencing.Hot spot in rpsL and 530 and 912 loop of rrsProportion method.About half of the isolates MDR    
288 Japan1999rrsMTB000019491 (C/T)1214972N/AN/AN/AN/ARFLP and sequencing.360 bp fragment of rpsLBroth Microdilution method.N.S.    
289 Japan1999rrsMTB000019512 (C/T)1214972N/AN/AN/AN/ARFLP and sequencing.360 bp fragment of rpsLBroth Microdilution method.N.S.    
292 Japan1999rrsMTB000019516 (C/T)1214972N/AN/AN/AN/ARFLP and sequencing.360 bp fragment of rpsLBroth Microdilution method.N.S.    
531 Japan1992-1994rrsMTB000019512 (C/T)463610000.00%0.00%Sequencing.Hot spot in rpsL and 530 and 912 loop of rrsAbsolute concentration method.N.S    
534 Japan1992-1994rrsMTB000019516 (C/T)463610000.00%0.00%Sequencing.Hot spot in rpsL and 530 and 912 loop of rrsAbsolute concentration method.N.S    
539 Japan1992-1994rrsMTB000019491 (C/T)463610000.00%0.00%Sequencing.Hot spot in rpsL and 530 and 912 loop of rrsAbsolute concentration method.N.S    
554 ChinaN.S.rrsMTB000019491 (C/T)52439000.00%0.00%PCR-SSCP, chip hybridization, and Sequencing. Hot spot in rpsL and 530 and 912 loop of rrsN.S.All PDR or MDR    
555 ChinaN.S.rrsMTB000019512 (C/T)52439000.00%0.00%PCR-SSCP, chip hybridization, and Sequencing. Hot spot in rpsL and 530 and 912 loop of rrsN.S.All PDR or MDR    
558 ChinaN.S.rrsMTB000019516 (C/T)52439000.00%0.00%PCR-SSCP, chip hybridization, and Sequencing. Hot spot in rpsL and 530 and 912 loop of rrsN.S.All PDR or MDR    
798 Japan2000-2003rrsMTB000019491 (C/T)986335000.00%0.00%Sequencing.Whole gene rpsL, 530 and 912 loop or rrsBACTEC 9600 MGIT.27 SM, 23 MDR, 11 PDR    
799 Japan2000-2003rrsMTB000019512 (C/T)9863358012.70%0.00%Sequencing.Whole gene rpsL, 530 and 912 loop or rrsBACTEC 9600 MGIT.27 SM, 23 MDR, 11 PDR    
802 Japan2000-2003rrsMTB000019516 (C/T)986335304.80%0.00%Sequencing.Whole gene rpsL, 530 and 912 loop or rrsBACTEC 9600 MGIT.27 SM, 23 MDR, 11 PDR    
865 Portugal2003rrsMTB000019491 (C/T)58517000.00%0.00%Sequencing.Whole genes or rpsL and rrsBACTEC 960. All MDR.    
866 Portugal2003rrsMTB000019512 (C/T)58517000.00%0.00%Sequencing.Whole genes or rpsL and rrsBACTEC 960. All MDR.    
869 Portugal2003rrsMTB000019516 (C/T)58517000.00%0.00%Sequencing.Whole genes or rpsL and rrsBACTEC 960. All MDR.    
996 China2002-2004rrsMTB000019491 (C/T)215115100000.00%0.00%DHPLC analysis and sequencing.Hot spot in rpsL, 530, 912 loop and 1400 region of rrsAbsolute concentration method.43 MDR    
997 China2002-2004rrsMTB000019512 (C/T)215115100000.00%0.00%DHPLC analysis and sequencing.Hot spot in rpsL, 530, 912 loop and 1400 region of rrsAbsolute concentration method.43 MDR    
1000 China2002-2004rrsMTB000019516 (C/T)215115100100.90%0.00%DHPLC analysis and sequencing.Hot spot in rpsL, 530, 912 loop and 1400 region of rrsAbsolute concentration method.43 MDR    
1095 BrazilN.S.rrsMTB000019491 (C/T)794732408.50%0.00%Sequencing. Hot spot in rpsL and 530 and 912 loop of rrsAbsolute concentration method.9 SM, 27 MDR, 11 PDR     
1096 BrazilN.S.rrsMTB000019512 (C/T)794732000.00%0.00%Sequencing. Hot spot in rpsL and 530 and 912 loop of rrsAbsolute concentration method.9 SM, 27 MDR, 11 PDR     
1099 BrazilN.S.rrsMTB000019516 (C/T)794732306.40%0.00%Sequencing. Hot spot in rpsL and 530 and 912 loop of rrsAbsolute concentration method.9 SM, 27 MDR, 11 PDR     
1104 Multiple countriesN.S.rrsMTB000019491 (C/T)1397861101.30%0.00%Sequencing.Whole genes or rpsL and rrsBACTEC and proportion method.N.S.    
1105 Multiple countriesN.S.rrsMTB000019512 (C/T)1397861101.30%0.00%Sequencing.Whole genes or rpsL and rrsBACTEC and proportion method.N.S.    
1108 Multiple countriesN.S.rrsMTB000019516 (C/T)1397861101.30%0.00%Sequencing.Whole genes or rpsL and rrsBACTEC and proportion method.N.S.    
1211 Singapore1994-1996rrsMTB000019491 (C/T)14810246000.00%0.00%Sequencing.Whole genes or rpsL and rrsBACTEC 460. N.S.    
1212 Singapore1994-1996rrsMTB000019512 (C/T)14810246000.00%0.00%Sequencing.Whole genes or rpsL and rrsBACTEC 460. N.S.    
1215 Singapore1994-1996rrsMTB000019516 (C/T)14810246202.00%0.00%Sequencing.Whole genes or rpsL and rrsBACTEC 460. N.S.    
1283 ChinaN.S.rrsMTB000019491 (C/T)574017030.00%0.00%PCR-SSCP and Sequencing.Hot spot in rpsL and 530 loop of rrsAbsolute concentration method.Both monoresistant, PDR and MDR isolates    
1284 ChinaN.S.rrsMTB000019512 (C/T)574017000.00%0.00%PCR-SSCP and Sequencing.Hot spot in rpsL and 530 loop of rrsAbsolute concentration method.Both monoresistant, PDR and MDR isolates    
1287 ChinaN.S.rrsMTB000019516 (C/T)574017000.00%0.00%PCR-SSCP and Sequencing.Hot spot in rpsL and 530 loop of rrsAbsolute concentration method.Both monoresistant, PDR and MDR isolates    
1308 China1999-2004rrsMTB000019491 (C/T)1679869000.00%0.00%RDBH, SSCP, RFLP and sequencing.Hot spot in rpsL, 530 loop of rrsAbsolute concentration method.12 S, 54 MDR, 32 PDR    
1309 China1999-2004rrsMTB000019512 (C/T)1679869000.00%0.00%RDBH, SSCP, RFLP and sequencing.Hot spot in rpsL, 530 loop of rrsAbsolute concentration method.12 S, 54 MDR, 32 PDR    
1324 China1999-2004rrsMTB000019516 (C/T)1679869101.00%0.00%RDBH, SSCP, RFLP and sequencing.Hot spot in rpsL, 530 loop of rrsAbsolute concentration method.12 S, 54 MDR, 32 PDR    

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