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STREPTOMYCIN [SM]


: rrs: MTB000019rpsL: Rv0682gidB: Rv3919c

MTB000019

More about MTB000019 on    TBDB.org

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Select interval to show only those mutations included. Selected interval is marked with a red color.
IDAdded byCountryTime periodSymbolGene IDMutationNo. of isolates testedNo. of isolates w/ mutationPercent tested w/ mutation Molecular detection method - gene coverageDST method - resistance pattern among R isolatesCommentsEditDeleteSelect
TotalRSRSRS
75 Poland2000rrsMTB000019513 (A/T)1038815000.00%0.00%Sequencing.Hot spot in rpsL and 530 and 912 loop of rrsBACTEC 460 and proportion method.N.S.    
272 IndiaN.S.rrsMTB000019513 (A/T)694920N/AN/AN/AN/ARFLP and sequencing.360 bp fragment of rpsLResistance ratio method and Absolute concentration method.N.S    
281 Germany, Sierra Leone1997rrsMTB000019513 (A/T)635013306.00%0.00%Sequencing.Hot spot in rpsL and 530 and 912 loop of rrsProportion method.About half of the isolates MDR    
290 Japan1999rrsMTB000019513 (A/T)1214972N/AN/AN/AN/ARFLP and sequencing.360 bp fragment of rpsLBroth Microdilution method.N.S.    
532 Japan1992-1994rrsMTB000019513 (A/T)4636108022.20%0.00%Sequencing.Hot spot in rpsL and 530 and 912 loop of rrsAbsolute concentration method.N.S    
556 ChinaN.S.rrsMTB000019513 (A/T)524395011.60%0.00%PCR-SSCP, chip hybridization, and Sequencing. Hot spot in rpsL and 530 and 912 loop of rrsN.S.All PDR or MDR    
800 Japan2000-2003rrsMTB000019513 (A/T)986335304.80%0.00%Sequencing.Whole gene rpsL, 530 and 912 loop or rrsBACTEC 9600 MGIT.27 SM, 23 MDR, 11 PDR    
867 Portugal2003rrsMTB000019513 (A/T)58517000.00%0.00%Sequencing.Whole genes or rpsL and rrsBACTEC 960. All MDR.    
998 China2002-2004rrsMTB000019513 (A/T)215115100000.00%0.00%DHPLC analysis and sequencing.Hot spot in rpsL, 530, 912 loop and 1400 region of rrsAbsolute concentration method.43 MDR    
1097 BrazilN.S.rrsMTB000019513 (A/T)794732102.10%0.00%Sequencing. Hot spot in rpsL and 530 and 912 loop of rrsAbsolute concentration method.9 SM, 27 MDR, 11 PDR     
1106 Multiple countriesN.S.rrsMTB000019513 (A/T)1397861000.00%0.00%Sequencing.Whole genes or rpsL and rrsBACTEC and proportion method.N.S.    
1213 Singapore1994-1996rrsMTB000019513 (A/T)14810246000.00%0.00%Sequencing.Whole genes or rpsL and rrsBACTEC 460. N.S.    
1285 ChinaN.S.rrsMTB000019513 (A/T)574017307.50%0.00%PCR-SSCP and Sequencing.Hot spot in rpsL and 530 loop of rrsAbsolute concentration method.Both monoresistant, PDR and MDR isolates    
1310 China1999-2004rrsMTB000019513 (A/T)1679869404.10%0.00%RDBH, SSCP, RFLP and sequencing.Hot spot in rpsL, 530 loop of rrsAbsolute concentration method.12 S, 54 MDR, 32 PDR    

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