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RIFAMPICIN [RIF]


rpoB: Rv0667embB: Rv3795

Rv0667

More about Rv0667 on    TBDB.org

More about Rv0667 on    TubercuList

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Select interval to show only those mutations included. Selected interval is marked with a red color.
IDAdded byCountryTime periodSymbolGene IDMutationNo. of isolates testedNo. of isolates w/ mutationPercent tested w/ mutation Molecular detection method - gene coverageDST method - resistance pattern among R isolatesCommentsEditDeleteSelect
TotalRSRSRS
2 Russia1997-2005rpoBRv0667S531L (TCG/TTG) O412271141177065.30%0.00%Primer extension minisequencing and sequencing.RRDR Absolute concentration method.11 R, 260 MDRP 4 isolates had both S531 L and H526Y, 1 isolate S531L and H526D, 1 isolate S531L and H526R mutations   
22 Russia1997-2005rpoBRv0667S522L (TCG/TTG)412271141000.00%0.00%Primer extension minisequencing and sequencing.RRDR Absolute concentration method.11 R, 260 MDRN 1 isolate had both L511P and D516G (GAC/GGC) mutations   
173 Hong Kong1994-2004rpoBRv0667S522L (TCG/TTG)30022179210.90%1.30%PCR-SSCP and Sequencing.RRDRAbsolute concentration method.6 R, 213 MDR, 2 PDR    
179 Hong Kong1994-2004rpoBRv0667S531L (TCG/TTG) T30022179136061.50%0.00%PCR-SSCP and Sequencing.RRDRAbsolute concentration method.6 R, 213 MDR, 2 PDRT 1 isolate had both S531L and Q513L and 1 isolate both S531L and H526D mutations   
345 Germany2001rpoBRv0667S522L (TCG/TTG)14310340201.90%0.00%Real-time PCR, MTBDR assay and Sequencing.RRDR 81bpBACTEC 460.All MDR    
351 Germany2001rpoBRv0667S531L (TCG/TTG) 1431034074071.80%0.00%Real-time PCR, MTBDR assay and Sequencing.RRDR 81bpBACTEC 460.All MDR    
498 Taiwan2007-2008rpoBRv0667S522L (TCG/TTG)27224230000.00%0.00%Sequencing.rpoBProportion method and MGIT 960. All MDR    
504 Taiwan2007-2008rpoBRv0667S531L (TCG/TTG) 27224230146060.30%0.00%Sequencing.rpoBProportion method and MGIT 960. All MDR    
510 Taiwan1998-2003rpoBRv0667S531L (TCG/TTG) 2021624075046.30%0.00%SequencingRRDR 541 bp regionN.S.All MDR    
517 Taiwan1998-2003rpoBRv0667S522L (TCG/TTG)20216240201.20%0.00%SequencingRRDR 541 bp regionN.S.All MDR    
709 Italy2002-2005rpoBRv0667S522L (TCG/TTG)20614264000.00%0.00%Oligobased hybridization assay and sequencing.RRDRBACTEC 460, MGIT 960 and proportion method.3 R, 139 MDR, 18 PDR     
715 Italy2002-2005rpoBRv0667S531L (TCG/TTG)2061426487061.30%0.00%Oligobased hybridization assay and sequencing.RRDRBACTEC 460, MGIT 960 and proportion method.3 R, 139 MDR, 18 PDR     
824 KoreaN.S.rpoBRv0667S522L (TCG/TTG)243115128201.70%0.00%Oligobased hybridization assay and sequencing.RRDR 511-533Proportion method.3 R, 112 MDR     
830 KoreaN.S.rpoBRv0667S531L (TCG/TTG)24311512860052.20%0.00%Oligobased hybridization assay and sequencing.RRDR 511-533Proportion method.3 R, 112 MDR     
899 Thailand2003-2005rpoBRv0667S522L (TCG/TTG)18415430201.30%0.00%MAS-PCR and Sequencing.rpoBProportion method. 11 R, 143 MDR.    
905 Thailand2003-2005rpoBRv0667S531L (TCG/TTG) 1841543087056.50%0.00%MAS-PCR and Sequencing.rpoBProportion method. 11 R, 143 MDR.    
1017 Russia2000-2002rpoBRv0667S522L (TCG/TTG)1701664100.60%0.00%Oligobased chip assay, PCR-SSCP and sequencing.RRDRAbsolute concentration method.All R monoresistant    
1023 Russia2000-2002rpoBRv0667S531L (TCG/TTG)170166497058.40%0.00%Oligobased chip assay, PCR-SSCP and sequencing.RRDRAbsolute concentration method.All R monoresistant    
1201 China2005-2006rpoBRv0667S522L (TCG/TTG)235102133000.00%0.00%Sequencing rpoBProportion method and MGIT 960. N.S.    
1207 China2005-2006rpoBRv0667S531L (TCG/TTG) 23510213341040.20%0.00%Sequencing rpoBProportion method and MGIT 960. N.S.    
1218 India2001-2003rpoBRv0667S522L (TCG/TTG)18714938000.00%0.00%Sequencing.RRDR 437bp fragmentProportion method.All MDR     
1224 India2001-2003rpoBRv0667S531L (TCG/TTG)1871493885057.00%0.00%Sequencing.RRDR 437bp fragmentProportion method.All MDR     
1234 Russia2000-2005rpoBRv0667S522L (TCG/TTG)29027218200.70%0.00%Oligobased chip assay, PCR-SSCP and sequencing.RRDRAbsolute concentration method.94% MDR    
1240 Russia2000-2005rpoBRv0667S531L (TCG/TTG)29027218176064.70%0.00%Oligobased chip assay, PCR-SSCP and sequencing.RRDRAbsolute concentration method.94% MDR    
1247 Vietnam2005rpoBRv0667S522L (TCG/TTG)15410450000.00%0.00%MAS-PCR, MTBDR assay and Sequencing.rpoBProportion method. 102 MDR    
1253 Vietnam2005rpoBRv0667S531L (TCG/TTG) 1541045046060.30%0.00%MAS-PCR, MTBDR assay and Sequencing.rpoBProportion method. 102 MDR    
1271 ChinaN.S.rpoBRv0667S522L (TCG/TTG)14211230000.00%0.00%Sequencing.rpoB and Rv2629Proportion method and MGIT 960. N.S.    
1277 ChinaN.S.rpoBRv0667S531L (TCG/TTG) 1421123035031.30%0.00%Sequencing.rpoB and Rv2629Proportion method and MGIT 960. N.S.    
1330 Hong Kong1999-2003rpoBRv0667S522L (TCG/TTG)32992163083200.90%0.00%dHPLC and Sequencing.RRDRAbsolute concentration method.Only information about R resistance     
1336 Hong Kong1999-2003rpoBRv0667S531L (TCG/TTG)32992163083112051.90%0.00%dHPLC and Sequencing.RRDRAbsolute concentration method.Only information about R resistance     

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