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rpoB: Rv0667embB: Rv3795


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Select interval to show only those mutations included. Selected interval is marked with a red color.
IDAdded byCountryTime periodSymbolGene IDMutationNo. of isolates testedNo. of isolates w/ mutationPercent tested w/ mutation Molecular detection method - gene coverageDST method - resistance pattern among R isolatesCommentsEditDeleteSelect
20 Russia1997-2005rpoBRv0667D516V (GAC/GTC) N4122711411806.60%0.00%Primer extension minisequencing and sequencing.RRDR Absolute concentration method.11 R, 260 MDRN 1 isolate had both L511P and D516G (GAC/GGC) mutations   
171 Hong Kong1994-2004rpoBRv0667D516V (GAC/GTC)30022179200.90%0.00%PCR-SSCP and Sequencing.RRDRAbsolute concentration method.6 R, 213 MDR, 2 PDR    
343 Germany2001rpoBRv0667D516V (GAC/GTC)14310340201.90%0.00%Real-time PCR, MTBDR assay and Sequencing.RRDR 81bpBACTEC 460.All MDR    
496 Taiwan2007-2008rpoBRv0667D516V (GAC/GTC)27224230602.50%0.00%Sequencing.rpoBProportion method and MGIT 960. All MDR    
515 Taiwan1998-2003rpoBRv0667D516V (GAC/GTC)20216240402.50%0.00%SequencingRRDR 541 bp regionN.S.All MDR    
707 Italy2002-2005rpoBRv0667D516V (GAC/GTC)206142641117.70%1.60%Oligobased hybridization assay and sequencing.RRDRBACTEC 460, MGIT 960 and proportion method.3 R, 139 MDR, 18 PDR     
822 KoreaN.S.rpoBRv0667D516V (GAC/GTC)2431151281008.70%0.00%Oligobased hybridization assay and sequencing.RRDR 511-533Proportion method.3 R, 112 MDR     
897 Thailand2003-2005rpoBRv0667D516V (GAC/GTC)184154301207.80%0.00%MAS-PCR and Sequencing.rpoBProportion method. 11 R, 143 MDR.    
1015 Russia2000-2002rpoBRv0667D516V (GAC/GTC)1701664603.60%0.00%Oligobased chip assay, PCR-SSCP and sequencing.RRDRAbsolute concentration method.All R monoresistant    
1199 China2005-2006rpoBRv0667D516V (GAC/GTC)235102133605.90%0.00%Sequencing rpoBProportion method and MGIT 960. N.S.    
1229 India2001-2003rpoBRv0667D516V (GAC/GTC)187149381107.40%0.00%Sequencing.RRDR 437bp fragmentProportion method.All MDR     
1232 Russia2000-2005rpoBRv0667D516V (GAC/GTC)290272181003.70%0.00%Oligobased chip assay, PCR-SSCP and sequencing.RRDRAbsolute concentration method.94% MDR    
1245 Vietnam2005rpoBRv0667D516V (GAC/GTC)154104501002.50%0.00%MAS-PCR, MTBDR assay and Sequencing.rpoBProportion method. 102 MDR    
1269 ChinaN.S.rpoBRv0667D516V (GAC/GTC)14211230201.80%0.00%Sequencing.rpoB and Rv2629Proportion method and MGIT 960. N.S.    
1328 Hong Kong1999-2003rpoBRv0667D516V (GAC/GTC)32992163083100.50%0.00%dHPLC and Sequencing.RRDRAbsolute concentration method.Only information about R resistance     

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