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RIFAMPICIN [RIF]


rpoB: Rv0667embB: Rv3795

Rv0667

More about Rv0667 on    TBDB.org

More about Rv0667 on    TubercuList

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Select interval to show only those mutations included. Selected interval is marked with a red color.
IDAdded byCountryTime periodSymbolGene IDMutationNo. of isolates testedNo. of isolates w/ mutationPercent tested w/ mutation Molecular detection method - gene coverageDST method - resistance pattern among R isolatesCommentsEditDeleteSelect
TotalRSRSRS
4 Russia1997-2005rpoBRv0667L533P (CTG/CCG) Q412271141401.50%0.00%Primer extension minisequencing and sequencing.RRDR Absolute concentration method.11 R, 260 MDR    
18 Russia1997-2005rpoBRv0667L511P ( CTG/CCG)412271141301.10%0.00%Primer extension minisequencing and sequencing.RRDR Absolute concentration method.11 R, 260 MDR    
169 Hong Kong1994-2004rpoBRv0667L511P ( CTG/CCG) S30022179200.90%0.00%PCR-SSCP and Sequencing.RRDRAbsolute concentration method.6 R, 213 MDR, 2 PDRS 1 isolate had both L511P and N518D (AAC/GAC) and 1 isolate both L511P and S512G (AGC/GGC) mutations   
181 Hong Kong1994-2004rpoBRv0667L533P (CTG/CCG) U30022179602.70%0.00%PCR-SSCP and Sequencing.RRDRAbsolute concentration method.6 R, 213 MDR, 2 PDRU 1 isolate had both L533P and N518D (AAC/GAC) mutations   
341 Germany2001rpoBRv0667L511P ( CTG/CCG)14310340000.00%0.00%Real-time PCR, MTBDR assay and Sequencing.RRDR 81bpBACTEC 460.All MDR    
353 Germany2001rpoBRv0667L533P (CTG/CCG) 14310340000.00%0.00%Real-time PCR, MTBDR assay and Sequencing.RRDR 81bpBACTEC 460.All MDR    
494 Taiwan2007-2008rpoBRv0667L511P ( CTG/CCG)27224230000.00%0.00%Sequencing.rpoBProportion method and MGIT 960. All MDR    
506 Taiwan2007-2008rpoBRv0667L533P (CTG/CCG) 272242301305.40%0.00%Sequencing.rpoBProportion method and MGIT 960. All MDR    
512 Taiwan1998-2003rpoBRv0667L533P (CTG/CCG) 20216240603.70%0.00%SequencingRRDR 541 bp regionN.S.All MDR    
513 Taiwan1998-2003rpoBRv0667L511P ( CTG/CCG)20216240000.00%0.00%SequencingRRDR 541 bp regionN.S.All MDR    
705 Italy2002-2005rpoBRv0667L511P ( CTG/CCG)20614264211.40%1.60%Oligobased hybridization assay and sequencing.RRDRBACTEC 460, MGIT 960 and proportion method.3 R, 139 MDR, 18 PDR     
717 Italy2002-2005rpoBRv0667L533P (CTG/CCG) W20614264322.10%3.10%Oligobased hybridization assay and sequencing.RRDRBACTEC 460, MGIT 960 and proportion method.3 R, 139 MDR, 18 PDR w 1 isolate had both D516Y andL533P mutations   
820 KoreaN.S.rpoBRv0667L511P ( CTG/CCG)243115128100.90%0.00%Oligobased hybridization assay and sequencing.RRDR 511-533Proportion method.3 R, 112 MDR     
832 KoreaN.S.rpoBRv0667L533P (CTG/CCG) 243115128322.60%1.60%Oligobased hybridization assay and sequencing.RRDR 511-533Proportion method.3 R, 112 MDR     
895 Thailand2003-2005rpoBRv0667L511P ( CTG/CCG)18415430000.00%0.00%MAS-PCR and Sequencing.rpoBProportion method. 11 R, 143 MDR.    
907 Thailand2003-2005rpoBRv0667L533P (CTG/CCG) 18415430301.90%0.00%MAS-PCR and Sequencing.rpoBProportion method. 11 R, 143 MDR.    
1013 Russia2000-2002rpoBRv0667L511P ( CTG/CCG)17016641408.40%0.00%Oligobased chip assay, PCR-SSCP and sequencing.RRDRAbsolute concentration method.All R monoresistant    
1025 Russia2000-2002rpoBRv0667L533P (CTG/CCG) 1701664100.60%0.00%Oligobased chip assay, PCR-SSCP and sequencing.RRDRAbsolute concentration method.All R monoresistant    
1196 China2005-2006rpoBRv0667L533P (CTG/CCG) 235102133302.90%0.00%Sequencing rpoBProportion method and MGIT 960. N.S.    
1197 China2005-2006rpoBRv0667L511P ( CTG/CCG)235102133000.00%0.00%Sequencing rpoBProportion method and MGIT 960. N.S.    
1226 India2001-2003rpoBRv0667L533P (CTG/CCG) 18714938604.00%0.00%Sequencing.RRDR 437bp fragmentProportion method.All MDR     
1227 India2001-2003rpoBRv0667L511P ( CTG/CCG)18714938201.30%0.00%Sequencing.RRDR 437bp fragmentProportion method.All MDR     
1230 Russia2000-2005rpoBRv0667L511P ( CTG/CCG)290272181304.80%0.00%Oligobased chip assay, PCR-SSCP and sequencing.RRDRAbsolute concentration method.94% MDR    
1242 Russia2000-2005rpoBRv0667L533P (CTG/CCG) 29027218501.80%0.00%Oligobased chip assay, PCR-SSCP and sequencing.RRDRAbsolute concentration method.94% MDR    
1243 Vietnam2005rpoBRv0667L511P ( CTG/CCG)15410450300.00%0.00%MAS-PCR, MTBDR assay and Sequencing.rpoBProportion method. 102 MDR    
1255 Vietnam2005rpoBRv0667L533P (CTG/CCG) 15410450505.40%0.00%MAS-PCR, MTBDR assay and Sequencing.rpoBProportion method. 102 MDR    
1267 ChinaN.S.rpoBRv0667L511P ( CTG/CCG)14211230302.70%0.00%Sequencing.rpoB and Rv2629Proportion method and MGIT 960. N.S.    
1279 ChinaN.S.rpoBRv0667L533P (CTG/CCG) 14211230000.00%0.00%Sequencing.rpoB and Rv2629Proportion method and MGIT 960. N.S.    
1326 Hong Kong1999-2003rpoBRv0667L511P ( CTG/CCG)32992163083672.80%0.20%dHPLC and Sequencing.RRDRAbsolute concentration method.Only information about R resistance     
1338 Hong Kong1999-2003rpoBRv0667L533P (CTG/CCG) 329921630831607.40%0.00%dHPLC and Sequencing.RRDRAbsolute concentration method.Only information about R resistance     

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