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rpoB: Rv0667embB: Rv3795


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Select interval to show only those mutations included. Selected interval is marked with a red color.
IDAdded byCountryTime periodSymbolGene IDMutationNo. of isolates testedNo. of isolates w/ mutationPercent tested w/ mutation Molecular detection method - gene coverageDST method - resistance pattern among R isolatesCommentsEditDeleteSelect
26 Russia1997-2005rpoBRv0667H526L (CAC/CTC)412271141200.70%0.00%Primer extension minisequencing and sequencing.RRDR Absolute concentration method.11 R, 260 MDRO 1 isolate had both S531W and H526L mutations   
177 Hong Kong1994-2004rpoBRv0667H526L (CAC/CTC)30022179210.90%1.30%PCR-SSCP and Sequencing.RRDRAbsolute concentration method.6 R, 213 MDR, 2 PDR    
349 Germany2001rpoBRv0667H526L (CAC/CTC)14310340302.90%0.00%Real-time PCR, MTBDR assay and Sequencing.RRDR 81bpBACTEC 460.All MDR    
502 Taiwan2007-2008rpoBRv0667H526L (CAC/CTC)27224230000.00%0.00%Sequencing.rpoBProportion method and MGIT 960. All MDR    
508 Taiwan1998-2003rpoBRv0667H526L (CAC/CTC)20216240503.10%0.00%SequencingRRDR 541 bp regionN.S.All MDR    
713 Italy2002-2005rpoBRv0667H526L (CAC/CTC)20614264100.70%0.00%Oligobased hybridization assay and sequencing.RRDRBACTEC 460, MGIT 960 and proportion method.3 R, 139 MDR, 18 PDR     
828 KoreaN.S.rpoBRv0667H526L (CAC/CTC)243115128403.50%0.00%Oligobased hybridization assay and sequencing.RRDR 511-533Proportion method.3 R, 112 MDR     
903 Thailand2003-2005rpoBRv0667H526L (CAC/CTC)18415430603.90%0.00%MAS-PCR and Sequencing.rpoBProportion method. 11 R, 143 MDR.    
1021 Russia2000-2002rpoBRv0667H526L (CAC/CTC)1701664000.00%0.00%Oligobased chip assay, PCR-SSCP and sequencing.RRDRAbsolute concentration method.All R monoresistant    
1205 China2005-2006rpoBRv0667H526L (CAC/CTC)23510213311010.80%0.00%Sequencing rpoBProportion method and MGIT 960. N.S.    
1222 India2001-2003rpoBRv0667H526L (CAC/CTC)18714938100.70%0.00%Sequencing.RRDR 437bp fragmentProportion method.All MDR     
1238 Russia2000-2005rpoBRv0667H526L (CAC/CTC)29027218100.40%0.00%Oligobased chip assay, PCR-SSCP and sequencing.RRDRAbsolute concentration method.94% MDR    
1251 Vietnam2005rpoBRv0667H526L (CAC/CTC)15410450100.00%0.00%MAS-PCR, MTBDR assay and Sequencing.rpoBProportion method. 102 MDR    
1275 ChinaN.S.rpoBRv0667H526L (CAC/CTC)142112301109.80%0.00%Sequencing.rpoB and Rv2629Proportion method and MGIT 960. N.S.    
1334 Hong Kong1999-2003rpoBRv0667H526L (CAC/CTC)32992163083502.30%0.00%dHPLC and Sequencing.RRDRAbsolute concentration method.Only information about R resistance     

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