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rpoB: Rv0667embB: Rv3795


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Select interval to show only those mutations included. Selected interval is marked with a red color.
IDAdded byCountryTime periodSymbolGene IDMutationNo. of isolates testedNo. of isolates w/ mutationPercent tested w/ mutation Molecular detection method - gene coverageDST method - resistance pattern among R isolatesCommentsEditDeleteSelect
1 Russia1997-2005rpoBRv0667H526N (CAC/AAC)412271141301.10%0.00%Primer extension minisequencing and sequencing.RRDR Absolute concentration method.11 R, 260 MDRO 1 isolate had both S531W and H526L mutations   
178 Hong Kong1994-2004rpoBRv0667H526N (CAC/AAC)30022179100.50%0.00%PCR-SSCP and Sequencing.RRDRAbsolute concentration method.6 R, 213 MDR, 2 PDR    
350 Germany2001rpoBRv0667H526N (CAC/AAC)14310340403.90%0.00%Real-time PCR, MTBDR assay and Sequencing.RRDR 81bpBACTEC 460.All MDR    
503 Taiwan2007-2008rpoBRv0667H526N (CAC/AAC)27224230000.00%0.00%Sequencing.rpoBProportion method and MGIT 960. All MDR    
509 Taiwan1998-2003rpoBRv0667H526N (CAC/AAC)20216240100.60%0.00%SequencingRRDR 541 bp regionN.S.All MDR    
714 Italy2002-2005rpoBRv0667H526N (CAC/AAC)20614264201.40%0.00%Oligobased hybridization assay and sequencing.RRDRBACTEC 460, MGIT 960 and proportion method.3 R, 139 MDR, 18 PDR     
829 KoreaN.S.rpoBRv0667H526N (CAC/AAC)243115128000.00%0.00%Oligobased hybridization assay and sequencing.RRDR 511-533Proportion method.3 R, 112 MDR     
904 Thailand2003-2005rpoBRv0667H526N (CAC/AAC)18415430000.00%0.00%MAS-PCR and Sequencing.rpoBProportion method. 11 R, 143 MDR.    
1022 Russia2000-2002rpoBRv0667H526N (CAC/AAC)1701664000.00%0.00%Oligobased chip assay, PCR-SSCP and sequencing.RRDRAbsolute concentration method.All R monoresistant    
1206 China2005-2006rpoBRv0667H526N (CAC/AAC)235102133000.00%0.00%Sequencing rpoBProportion method and MGIT 960. N.S.    
1223 India2001-2003rpoBRv0667H526N (CAC/AAC)18714938000.00%0.00%Sequencing.RRDR 437bp fragmentProportion method.All MDR     
1239 Russia2000-2005rpoBRv0667H526N (CAC/AAC)29027218000.00%0.00%Oligobased chip assay, PCR-SSCP and sequencing.RRDRAbsolute concentration method.94% MDR    
1252 Vietnam2005rpoBRv0667H526N (CAC/AAC)15410450200.00%0.00%MAS-PCR, MTBDR assay and Sequencing.rpoBProportion method. 102 MDR    
1276 ChinaN.S.rpoBRv0667H526N (CAC/AAC)14211230302.70%0.00%Sequencing.rpoB and Rv2629Proportion method and MGIT 960. N.S.    
1335 Hong Kong1999-2003rpoBRv0667H526N (CAC/AAC) AC32992163083301.40%0.00%dHPLC and Sequencing.RRDRAbsolute concentration method.Only information about R resistance AC 1 isolate had both H526N and L511P mutations   

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