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FLUOROQUINOLONES [FLQ]


gyrB: Rv0005gyrA: Rv0006

Rv0006

More about Rv0006 on    TBDB.org

More about Rv0006 on    TubercuList

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Select interval to show only those mutations included. Selected interval is marked with a red color.
IDAdded byCountryTime periodSymbolGene IDMutationNo. of isolates testedNo. of isolates w/ mutationPercent tested w/ mutation Molecular detection method - gene coverageDST method - resistance pattern among R isolatesCommentsEditDeleteSelect
TotalRSRSRS
37 ChinaN.S.gyrARv0006S91P (TCG/CCG)754233000.00%0.00%Sequencing, PCR-SSCP.QRDR of gyrAProportion method.All monoresistant    
48 RussiaN.S.gyrARv0006S91P (TCG/CCG)18567118609.00%0.00%Oligobased chip assay and sequencing.QRDR of gyrA Absolute concentration method.N.S    
124 Hong Kong1994-2004gyrARv0006S91P (TCG/CCG)25071179405.60%0.00%PCR-SSCP and Sequencing.QRDR of gyrAAbsolute concentration method.69 MDR, 2 PDR    
258 Hong Kong1991-2000gyrARv0006S91P (TCG/CCG)1385583407.30%0.00%PCR-SSCP and sequencing.gyrA: 320bp fragmentAbsolute concentration and broth macrodilution methods.Among 138 isolates 92 were MDR, among these 55 were O resistant    
522 Hong Kong1999-2003gyrARv0006S91P (TCG/CCG)553520102.90%0.00%Sequencing.QRDR of gyrAAbsolute concentration method and BACTEC MGIT 960.24 MDR, 11 O or PDR* Sequencing was preformed for isolates with OFL MIC >= 4 ug/ml, MIC <= 2ug/ml was defined as OFL sensitive   
541 SingaporeN.S.gyrARv0006S91P (TCG/CCG)1005347000.00%0.00%Sequencing.QRDR of gyrA and gyrBBACTEC 460 radiometric method.Resistant to at least one drug (H, R, S, E)    
720 Russia2006gyrARv0006S91P (TCG/CCG)704822000.00%0.00%Sequencing.QRDR of gyrA and gyrBAbsolute concentration method.45 XDR, 3 MDR    
806 South Korea2004gyrARv0006S91P (TCG/CCG)736310609.50%0.00%Sequencing.QRDR of gyrA and gyrBProportion method.All O resistant and different patterns of resistance to other FLQs    
984 China2002-2003gyrARv0006S91P (TCG/CCG) AF109872210111.50%4.50%DHPLC and Sequencing.gyrA: codon 74-95Absolute concentration method.Only information about O resistanceAF 9 isolates had both S91P and A90V mutations   
1004 India1995-1998gyrARv0006S91P (TCG/CCG)1286959101.40%0.00%Sequencing.gyrA: codon 89-95 and fragment of gyrBProportion method.18 O, 18 MDR, 33 PDR    
1187 IndiaN.S.gyrARv0006S91P (TCG/CCG)1187246101.40%0.00%Sequencing.QRDR of gyrA and gyrBAbsolute concentration method.38 O, 31 MDR, 2 PDR    
1265 Vietnam2005-2006gyrARv0006S91P (TCG/CCG)824240102.40%0.00%Sequencing.QRDR of gyrA Proportion method.N.S    
1349 ChinaN.S.gyrARv0006S91P (TCG/CCG)684424000.00%0.00%PCR-SSCP and Sequencing.QRDR of gyrAAbsolute concentration method.Only information about O resistance    

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